Protein Alignment CG32344 and Prp5

DIOPT Version :10

• Sequence 1: NP_612028.4
• Gene: CG32344 / 326208
• FlyBaseID: FBgn0052344
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 776
• Identity: 199/776 - (25%)
• Similarity: 327/776 - (42%)
• Gaps: 143/776 - (18%)

  Fly     2 RKKQADEIPGFPSLDNDAGTSDRGADILKSKSKKNKSGGFQSMGLGF-ELIK-----GITKR--- 57
            ||....|:|..        |....||:.|.:|...   |.|..|.|. :.||     |::|:
  Fly   470 RKNFYVEVPEL--------TRMTAADVEKYRSDLE---GIQVKGKGCPKPIKTWAQCGVSKKEME 523

  Fly    58 -----GYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKL---QRREPTKGARALI 114
                 |::.|||||.:.||.|:.|||::.:||||||||..|::|:|..:   ...|...||.|:|
  Fly   524 VLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAIAII 588

  Fly   115 LSPTRELAVQTYKFIKELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFLHLCVEMD- 178
            ::|||||.:|..|.|::..:.:.|:.:.|.||..:..|.:.:....::||.||||.:.:.....
  Fly   589 MAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSG 653

  Fly   179 --LKLNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMFSATLPKLLVEFARAGLNDPVL 241
              ..|..:.|||.|||||:|:|||..|:...:..:...|||||||||.|:.:...||..|..|:.
  Fly   654 RVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALARRILKKPIE 718

  Fly   242 IRLDVESKLPDALALKFLYCRPDDRYTALVVLLKYVIPVQSQTVVFAGTQHHVELISYILTEAGI 306
            :.:...|.:...:....:....|.::..|:.||. :.......:||...|.:.:::...|.:|..
  Fly   719 VIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLG-IYQEAGSIIVFVDKQENADILLRDLMKASY 782

  Fly   307 SNASVYSSLDPAARKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLFVHRVGR 371
            ...|::..:|...|......|.:.||.:||.|.|||||:|:..|..|||...|...:.:|||.||
  Fly   783 PCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGR 847

  Fly   372 CARAGRTGTAYSIVSTDDTAHLLDLHLFLNRPFNIHDSSALGT-IPQDL--LEEEHLTVTDIK-K 432
            ..|||:.|:||:.::.:.:.:..|:         |......|| ||.:|  |..|:..:.:.: |
  Fly   848 TGRAGKKGSAYTFITPEQSRYAGDI---------IRAMDLSGTLIPAELQALWTEYKALQEAEGK 903

  Fly   433 SHHIAGVL--------RTSENAYKKYLSSRPVA------------STDANARVKKIKFFALKPLE 477
            :.|..|..        ....||.|:....:..|            ..|.:.::::| |.|.:.::
  Fly   904 TVHTGGGFSGKGFKFDEQEFNAAKESKKLQKAALGLADSDDEEDIEQDIDQQIEQI-FAAKRTVK 967

  Fly   478 DFFTAAPVLAQAAEASG-------------QSTESQAKVSAAERK-------------------- 509
            |...||...|.||.|:.             .|..:||..:||...
  Fly   968 DTSAAATAAAAAAAAAAAAAAAVSGANPALASAAAQAAAAAAAANIAIAAASAPAAAGGAPSVAM 1032

  Fly   510 ---LQEEKHDILVKMRSFRPGGTVFELNTTQK--STQFIVMKEKRMQHAEVINKFRQQRAEEDID 569
               |..:|.::..::.|        ::|:::.  :...:|..|..::...|............:.
  Fly  1033 GGALSSDKLELAKRLAS--------KINSSKNLDTKGSVVTVEPMIKGPHVTGAAATLLTARTVA 1089

  Fly   570 EEKKTIEALNPSSGRMPTADEEAISSTFNKVVAPKRLQNMDALYKDKPKKKKRKINSKD------ 628
            |:...  .||......|..|||.:.........|......:....|.|::.:.|:.||:
  Fly  1090 EQMAA--KLNNKLNYQPKEDEEGLGPLVGGTTNPFTKYEEELEINDFPQQARWKVTSKEALAQIS 1152

  Fly   629 ---------EDHYVPYQSADKHTEDG-----LAINN-FERQAQNAEFSVSDRDLSQEVKHK 674
                     ...|||   ..|:..||     |||.: .|...|.|:     |::::.:|.:
  Fly  1153 EYSEAGLTVRGTYVP---QGKNPPDGERKLYLAIESCSELAVQKAK-----REITRLIKEE 1205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32344	NP_612028.4	DEADc_DDX54	39..243	CDD:350717	83/223 (37%)
		SrmB	41..449	CDD:440279	137/439 (31%)
		DBP10CT	<679..721	CDD:462373
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653
		DEAD-like_helicase_N	454..899	CDD:475120	142/449 (32%)
		KH-I_DDX46	1121..1223	CDD:411901	20/93 (22%)