DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32344 and ddx-27

DIOPT Version :9

Sequence 1:	NP_612028.4	Gene:	CG32344 / 326208	FlyBaseID:	FBgn0052344	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_490891.2	Gene:	ddx-27 / 171743	WormBaseID:	WBGene00022148	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	755	Identity:	206/755 - (27%)
Similarity:	320/755 - (42%)	Gaps:	178/755 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RKKQADEIPGFPSLDNDAGTSDRGADILKSKSKKNKSGGFQSMGLGFELIKGITKRGYKVPTPIQ 66
            :.|::.|...|.|...|..:.|...::           .|:.|.|..:::|..:..||..|||||
Worm   122 KSKKSQENEDFFSALIDGKSLDTSVNV-----------SFEQMNLSRQILKACSGAGYSDPTPIQ 175

  Fly    67 RKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKLQRREPTKGA---RALILSPTRELAVQTYKF 128
            :..||:.|.|:|:.|.|.||:||||.|::|:.|::..|  .|||   |.|:|.||||||:|.::.
Worm   176 QACIPVALTGKDICACAATGTGKTAAFVLPILERMIYR--PKGASCTRVLVLVPTRELAIQVFQV 238

  Fly   129 IKELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFL-HLCVEMDLKLNSIEYVVFDEA 192
            .::|..|::|:..|..||..:.:|.:|:.:.|||:||||||.: ||.......|::||.:|.|||
Worm   239 FRKLSTFIQLEVCLCAGGLDLKAQEAALRSGPDVVVATPGRLIDHLHNSPSFNLSNIEVLVLDEA 303

  Fly   193 DRLFEMGFGEQLNETLHRLPSSRQTVMFSATLPKLLVEFARAGLNDPVLIRLDVESKLPDALALK 257
            ||:.|..|.:|:||.:.....:|||::||||:.:.:.|.|...|..||.|.::..:.....|..:
Worm   304 DRMLEEAFRDQMNELIRLCAQNRQTLLFSATMTEEIDELASMSLQKPVKIFINENTDTALKLRQE 368

  Fly   258 FLYC---RPDDRYTALVVLLKYVIPVQSQTVVFAGTQHHVELISYILTEAGISNASVYSSLDPAA 319
            |:..   |..||...:..|:....  |:.|:||..|:...:.:..:|...||....:.|||....
Worm   369 FIRIRAGRETDREAMVAALVTRTF--QTNTIVFVRTKKDCQRMQILLGLLGIKVGQMQSSLTQGQ 431

  Fly   320 RKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLFVHRVGRCARAGRTGTAYSI 384
            |..:.:||...::.||:.||:|:||:||..:..|:|::.|...|.::|||||.||||:.|.:.|:
Worm   432 RIESLSKFKKAEIDVLVSTDLASRGLDIEGVQTVINMNMPKSIKQYIHRVGRTARAGKAGRSISL 496

  Fly   385 VSTDDTAHLLDLHLFLNRPFNIHDSSALGTIPQDLLEEEHLTVTDIKKSHHIAGVLRTSENAYKK 449
            |..|:...|.:          |.:|:|..|:.|.|:..|.:                   .||::
Worm   497 VGEDERKLLKE----------IVNSNADRTLKQRLVAPEVV-------------------EAYRR 532

  Fly   450 YLS--SRPVASTDANARVKKIKFFALKPLEDFFTAAPVLAQAAEASGQSTESQAKV-----SAAE 507
            .:.  ...:...|...|.:|                  ..:.||||...|::..:|     :.||
Worm   533 RIDELEETIQQIDEEDRAEK------------------ELRIAEASMAKTQNALEVGENGGAPAE 579

  Fly   508 RKLQEEKHDILVKMRSFRPGGTVFELNTTQKSTQFIVMKEKRMQHAEVINKFRQQRAEEDIDEE- 571
            |::...|...:.|.|.                     .:|||....:...|....:..|||..|
Worm   580 RRVWMMKESQIEKQRK---------------------REEKRQMKVDARKKAEAAKTPEDIQIEH 623

  Fly   572 ----------------KKTIEALNPSSGRMPTADEEAISSTFNKVVAPKRLQNMDALYKDKPKKK 620
                            .|.|.|:..|:|...               |.|..||          ||
Worm   624 EAAFHVRAAKRARHSKNKRIRAVVESAGTKG---------------AGKAAQN----------KK 663

  Fly   621 KRKINSKDEDHYVPYQSADKHTEDGLAINNFERQAQNAEFSVSDRDLSQEVKHKPGLKK-----W 680
            |...|||.....:|            .:|...|..|.|:..           .|||.||     .
Worm   664 KASSNSKTSLRDIP------------LVNAGSRGVQKAQKG-----------QKPGAKKGFTSAL 705

  Fly   681 DRIKKKMVSV-----QDPRANKIRTESGAWIPASFKTGRY 715
            ..:.||.|..     :|.:..|.|      :....||.:|
Worm   706 ASVSKKSVKAARHGPEDSKFQKAR------VAHRMKTKKY 739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32344	NP_612028.4	DEADc	41..243	CDD:238167	86/205 (42%)
		DEXDc	54..243	CDD:214692	82/192 (43%)
		HELICc	263..384	CDD:238034	40/120 (33%)
		DBP10CT	666..721	CDD:285373	14/60 (23%)
ddx-27	NP_490891.2	SrmB	128..609	CDD:223587	166/563 (29%)
		DEADc	150..354	CDD:238167	86/205 (42%)
		Helicase_C	379..488	CDD:278689	37/110 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D268859at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920