DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11583 and bxdc2

DIOPT Version :9

Sequence 1:	NP_001033989.1	Gene:	CG11583 / 326206	FlyBaseID:	FBgn0035524	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001166027.1	Gene:	bxdc2 / 402823	ZFINID:	ZDB-GENE-060518-1	Length:	383	Species:	Danio rerio

Alignment Length:	324	Identity:	160/324 - (49%)
Similarity:	212/324 - (65%)	Gaps:	23/324 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LPPQRSSDDVVPKKEKWVNKQRVLVFSARGISHRDRHLMKDIKTLMPHHRPESKMERSKTLSVVN 91
            :||..|:.       ||.||:||||||:||||.|.||||:|:||||||.|.::||:|...|.|||
Zfish    83 VPPPVSAG-------KWTNKERVLVFSSRGISFRTRHLMQDLKTLMPHSRADTKMDRKDKLFVVN 140

  Fly    92 EMCEMKHCNKAMLFEGRRKRDLYMWISNTSGSTGPSAKFLIENIHTMAELKMTGNCLRGSRPLLS 156
            |:||:|:|||.:.||.::|:||||||||.  ..|||.|||::|:||:||||||||||:|||||||
Zfish   141 EVCEIKNCNKCIFFEAKKKQDLYMWISNV--PHGPSVKFLVQNVHTLAELKMTGNCLKGSRPLLS 203

  Fly   157 FDSKFDELPHLKLLKELFVQTYSVPNHHPKSQPFVDHVFTFTYLDKRIWFRNFQILSEDGGLSEV 221
            ||..||..|...||||||.|.:|.|.||||||||||||.:|:..|.||||||:||:.||..|.|:
Zfish   204 FDPAFDSEPQYALLKELFTQVFSTPLHHPKSQPFVDHVISFSIADHRIWFRNYQIVEEDASLVEI 268

  Fly   222 GPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQRQVLKKAAKDKYVNRVEQKVKHEATRPIRAYD 286
            |||:|:||::||.|||.|.|::|||.:.||:..|::|:.||..:...|  |.||.     :|...
Zfish   269 GPRFVLNPIRIFQGSFGGPTLYENPHFQSPNAHRRMLRLAAAARQKER--QMVKQ-----VRMEK 326

  Fly   287 GMDNDELFEDDDPVETAKILAAIAKKKKEEAAKQTPKSALTKKIKEKQLQAVKDVIERKKARTI 350
            .|:...|.:.|       :..|:.....|..|.:.......||.|::..:..|..:.:||..::
Zfish   327 RMEECVLLQPD-------LTEAVFNTPAEPKAPRPEAPGPQKKKKKRLTELKKKTLMKKKGLSV 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11583	NP_001033989.1	Brix	43..290	CDD:294606	145/246 (59%)
bxdc2	NP_001166027.1	Brix	92..336	CDD:294606	146/252 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581742
Domainoid	1	1.000	252	1.000	Domainoid score	I2049
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10133
Inparanoid	1	1.050	313	1.000	Inparanoid score	I2560
OMA	1	1.010	-	-		QHG54029
OrthoDB	1	1.010	-	-		D495605at33208
OrthoFinder	1	1.000	-	-		FOG0004244
OrthoInspector	1	1.000	-	-		oto41267
orthoMCL	1	0.900	-	-		OOG6_101913
Panther	1	1.100	-	-	LDO	PTHR13634
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2983
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910