Protein Alignment TTLL1B and TTLL4

DIOPT Version :10

• Sequence 1: NP_729025.1
• Gene: TTLL1B / 326203
• FlyBaseID: FBgn0052238
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: XP_016860876.1
• Gene: TTLL4 / 9654
• HGNCID: 28976
• Length: 1226
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 112/348 - (32%)
• Similarity: 174/348 - (50%)
• Gaps: 58/348 - (16%)

  Fly   102 DDDWHFYWAGVQTCRNIFSVDSGYRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPL 166
            :|||...|.......:..|:      .::|.:||||..:::.|||.|.:|:.|.:   .|.|
Human   634 NDDWLGCWGHHMKSPSFRSI------REHQKLNHFPGSFQIGRKDRLWRNLSRMQ---SRFG--- 686

  Fly   167 AEKTESNNSSGTRYLYLDFVPTTFVLPADYNMFVEEYRKFPLSTWIMKPCGKSQGAGIFLINKLS 231
              |.|           ..|.|.:|:||.|..:..:.:.......||:||...::|.||.:|:|.|
Human   687 --KKE-----------FSFFPQSFILPQDAKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWS 738

  Fly   232 KLKKWSREAKGPFHPQIAKESYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRF 296
            :|.|              :...::.||:..|.||.|.|||||:||.|.|:.||:.|||..|..||
Human   739 QLPK--------------RRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRF 789

  Fly   297 CTVKYDTSVTELDNMYVHLTNVSVQKHGGEYN------TLHGGKWSVQNLALYLEGTRGKEVTDR 355
            .:.||..|:..|.|.::||||.||.|...||.      ...|.||:::.|..|| ..:|.. :|.
Human   790 ASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALWNYL-SQKGVN-SDA 852

  Fly   356 LFGAISWLIVHSLRAVAPVMAS--------DRHCFECYGYDIIIDNALKPWLVEVNASPSLTSTT 412
            ::..|..::|.::.:..|.:.|        ...|.|.:|:||::|..||||::|||.||||.|::
Human   853 IWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSS 917

  Fly   413 VNDRILKYKLIDNILSV---VLP 432
            ..|..:|.::|.::|::   |||
Human   918 PLDISIKGQMIRDLLNLAGFVLP 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1B	NP_729025.1	TTL	126..438	CDD:397308	107/324 (33%)
TTLL4	XP_016860876.1	TTL	654..946	CDD:397308	107/322 (33%)