DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TTLL1B and Ttll3

DIOPT Version :9

Sequence 1:	NP_729025.1	Gene:	TTLL1B / 326203	FlyBaseID:	FBgn0052238	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_038963762.1	Gene:	Ttll3 / 362415	RGDID:	1311255	Length:	1031	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	109/486 - (22%)
Similarity:	183/486 - (37%)	Gaps:	148/486 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 CTDLDKSVLVNNFEKRGWHQVNGDDDWHFYWAGVQTCRNIFSV--------DSGYRMHDNQMINH 135
            |..|.|..::|::.:.|           .:...|..|.|:.::        ||           .
  Rat   308 CRFLSKDQMINHYARAG-----------SFTTKVGLCLNLRNLPWFDEADADS-----------F 350

  Fly   136 FPNHYELSRKD-------------------LLVK--------NIKRYRKDLERDGNPLAEKTE-- 171
            ||..|.|..:|                   |:||        .|:...::...|..|..::.:
  Rat   351 FPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKLEGRSQSIPIQAREEEALEDTQPKKQEKKPV 415

  Fly   172 --------------SNNSSGTRYLYLDFVPTT--FVLPADYNMFVEEYRKF-----------PLS 209
                          ..:.|...:..:|..|..  ::.|.|:::|::.|.:.           |.|
  Rat   416 TVSSDFVDEALSACEEHLSNIAHKDIDKDPNAPLYLSPDDWSLFLQRYYQIVQPHSPQVLLSPYS 480

  Fly   210 ------------------------------------TWIMKPCGKSQGAGIFLINKLSKLKKWSR 238
                                                .||:||..||:|.||..::.|.::.|..
  Rat   481 QGAELRYLEVQVQRCEDILQQLRAVVPQIDMEGDRNIWIVKPGAKSRGRGITCMDHLDEMLKLV- 544

  Fly   239 EAKGPFHPQIAKE-SYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYD 302
                ..:|.:.|: .:::.:||:.||||.|.|||||.:.||..:.||..:.::..:.||.|..:
  Rat   545 ----DCNPMLMKDGKWIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF- 604

  Fly   303 TSVTELDNMYVHLTNVSVQKHGGEYNTLH-----GGKWSVQNLALYL-EGTRGKEVTDRLFGAIS 361
             |:..|||. |||.|.|:|:|.......|     ...||.|....:| |....|..:..:...:.
  Rat   605 -SLKNLDNS-VHLCNNSIQRHLEASCHRHPMLPPDNMWSSQRFQAHLQEVDAPKAWSTVIVPGMK 667

  Fly   362 WLIVHSLRAVAPVMASDRHCFECYGYDIIIDNALKPWLVEVNASPSLT-STTVNDRILKYKLIDN 425
            ..::|:|:.....:...:..||.||.|.:.....:|||:|:||||::. ||.|..|:......|.
  Rat   668 AAVIHALQTSQDNVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADT 732

  Fly   426 ILSVVLPPDGVPDVRWNKVPSADALGNFELL 456
            :..|:       |.|.::  |.|. |.|||:
  Rat   733 LRVVI-------DRRMDR--SCDT-GAFELI 753

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1B	NP_729025.1	TTL	126..438	CDD:281171	91/411 (22%)
Ttll3	XP_038963762.1	TTL	439..743	CDD:397308	81/318 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810