DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TTLL1B and Ttll13

DIOPT Version :9

Sequence 1:	NP_729025.1	Gene:	TTLL1B / 326203	FlyBaseID:	FBgn0052238	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_006540976.1	Gene:	Ttll13 / 269954	MGIID:	1920845	Length:	849	Species:	Mus musculus

Alignment Length:	404	Identity:	119/404 - (29%)
Similarity:	181/404 - (44%)	Gaps:	76/404 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 SVTNGNSNSGANSG--GGASGGAQGHDKLKIGFCTDLDKSVLVNNFEKRGWHQVNGDDDWHFYWA 110
            ::||....|....|  .|...|:           .||..|.:....:..|..:|..|::|..||.
Mouse    91 NLTNCKYESARVPGFMAGTQAGS-----------VDLPVSTVRRAAQMCGLKEVGEDEEWTVYWT 144

  Fly   111 GVQTCRNIFSVDSGYRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNS 175
            ....     |::....|...|.|||||...|:.|||||.:|:.|.:|         ...||.|
Mouse   145 DCSV-----SLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMQK---------LYPTEYN-- 193

  Fly   176 SGTRYLYLDFVPTTFVLPADYNMFVEEYRKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREA 240
                     ..|.|:.|||||..|....|:....|:|.||....||.|||:.....::|
Mouse   194 ---------IFPRTWCLPADYGDFQAYGRQRKTRTYICKPDSGCQGRGIFITRTPKEIK------ 243

  Fly   241 KGPFHPQIAKESYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKY-DTS 304
                    ..|..:..:||..|.||.|.|||:|:|||:.|..||:.:::::|..||.|:.| :.|
Mouse   244 --------PGEHMICQQYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLARFATMPYVEPS 300

  Fly   305 VTELDNMYVHLTNVSVQKHGGEY--NTLHGGKWSVQNLALYLEGTRGKEVTDRLFGAISWLIVHS 367
            ...|:.:.:||||.::.||...:  :...|.|..:..|..:|.  ........|:|.|..:|:.:
Mouse   301 HNNLEEVCMHLTNYAINKHNENFVRDDAVGSKRKLSTLNAWLR--EHSHDPQELWGDIEDIIIKT 363

  Fly   368 LRAVAPVMASDRH----------------CFECYGYDIIIDNALKPWLVEVNASPSLTSTTVNDR 416
            :.:...|:   ||                |||..|:||::|:.|||||:|||.|||.|:.:..||
Mouse   364 IISAHSVL---RHNYRTCFPQYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSRLDR 425

  Fly   417 ILKYKLIDNILSVV 430
            .:|..|:.:.:::|
Mouse   426 EVKDALLCDAMNLV 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1B	NP_729025.1	TTL	126..438	CDD:281171	103/324 (32%)
Ttll13	XP_006540976.1	TTL	154..439	CDD:281171	102/323 (32%)
Ttll13	XP_006540976.1	DNA_S_dndD	<466..635	CDD:274475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910