Protein Alignment TTLL1B and TTLL3

DIOPT Version :9

• Sequence 1: NP_729025.1
• Gene: TTLL1B / 326203
• FlyBaseID: FBgn0052238
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001021100.3
• Gene: TTLL3 / 26140
• HGNCID: 24483
• Length: 915
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 114/462 - (24%)
• Similarity: 184/462 - (39%)
• Gaps: 121/462 - (26%)

  Fly    70 GHDKLKIGFCTDLDK-----SVLVNNFEKRGWHQVNGDDDWHF---YWAGVQTCRNIFS--VDSG 124
            |...|.:|.|.:|..     .|..|:|..|.:.....||...|   :|  :...||:..  |.|.
Human   243 GTHALMVGLCLNLRNLPWFDEVDANSFFPRCYCLGAEDDKKAFIEDFW--LTAARNVLKLVVKSE 305

  Fly   125 YRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTE---------SNNSSGTRY 180
            ::.:..|.:.      |.:..|   |..|:..|      ||:....|         ....|...:
Human   306 WKSYPIQAVE------EEASGD---KQPKKQEK------NPVLVSPEFVDEALCACEEYLSNLAH 355

  Fly   181 LYL--DFVPTTFVLPADYNMFVEEYRKF--------PLST------------------------- 210
            :.:  |.....::.|..:::|::.|.:.        .|.|
Human   356 MDIDKDLEAPLYLTPEGWSLFLQRYYQVVHEGAELRHLDTQVQRCEDILQQLQAVVPQIDMEGDR 420

  Fly   211 --WIMKPCGKSQGAGIFLINKLSKLKKWSREAKGPFHPQIAKE-SYVISRYIDNPLLIGGKKFDL 272
              ||:||..||:|.||..::.|.::.|.   ..|  :|.:.|: .:|:.:||:.||||.|.||||
Human   421 NIWIVKPGAKSRGRGIMCMDHLEEMLKL---VNG--NPVVMKDGKWVVQKYIERPLLIFGTKFDL 480

  Fly   273 RLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKHGGEYNTLH------ 331
            |.:.||..:.||..:.::..:.||.|..:  |:..|||. |||.|.|:|||  ..|:.|
Human   481 RQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSIQKH--LENSCHRHPLLP 540

  Fly   332 -GGKWSVQNLALYLEGTRGKEVTDRLFGAISW----------LIVHSLRAVAPVMASDRHCFECY 385
             ...||.|....:|:         .:....:|          .::|:|:.....:...:..||.|
Human   541 PDNMWSSQRFQAHLQ---------EMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFELY 596

  Fly   386 GYDIIIDNALKPWLVEVNASPSLT-STTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADA 449
            |.|.:.....:|||:|:||||::. ||.|..|:......|.:..|:   |.:.|      .:.|.
Human   597 GADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVI---DRMLD------RNCDT 652

  Fly   450 LGNFELL 456
             |.|||:
Human   653 -GAFELI 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1B	NP_729025.1	TTL	126..438	CDD:281171	91/376 (24%)
TTLL3	NP_001021100.3	TTL	356..648	CDD:281171	82/319 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810