Protein Alignment TTLL1B and TTLL8

DIOPT Version :10

• Sequence 1: NP_729025.1
• Gene: TTLL1B / 326203
• FlyBaseID: FBgn0052238
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: XP_024307940.1
• Gene: TTLL8 / 164714
• HGNCID: 34000
• Length: 776
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 82/325 - (25%)
• Similarity: 139/325 - (42%)
• Gaps: 57/325 - (17%)

  Fly   139 HYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNSSGTRYLYLDFVPTTFVLPADYNMFVEEY 203
            :|.|...|..:.|.:.|....:...|.:.......:..|.|
Human   308 YYSLVHGDAFISNSRNYFSQCQALLNRITSVNPQTDIDGLR------------------------ 348

  Fly   204 RKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREAKGPFHPQIAKESYVISRYIDNPLLIGGK 268
                 :.||:||..||:|..|..::::.::    .|.....||......:|:.:||:.||||...
Human   349 -----NIWIIKPAAKSRGRDIVCMDRVEEI----LELAAADHPLSRDNKWVVQKYIETPLLICDT 404

  Fly   269 KFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKH----GGEYNT 329
            |||:|.:.||..:.||..:.:|:.:.||.|.::  |:.:||:. :||.|.:|||:    .|....
Human   405 KFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRF--SLDKLDSA-IHLCNNAVQKYLKNDVGRSPL 466

  Fly   330 LHG-GKWSVQNLALYLEGT-RGKEVTDRLFGAISWLIVHSLRAVAPVMASDRHCFECYGYDIIID 392
            |.. ..|:......||:.. ||......::.::...|.|:::.....:...::.||.||.|.::.
Human   467 LPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRKNSFELYGADFVLG 531

  Fly   393 NALKPWLVEVNASPSL-TSTTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADALGNFELL 456
            ...:|||:|:|:||:: .||.|..::......|.|...|   |...|:           ||||||
Human   532 RDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVAV---DRSCDI-----------GNFELL 582

  Fly   457  456
            Human   583  582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1B	NP_729025.1	TTL	126..438	CDD:397308	75/305 (25%)
TTLL8	XP_024307940.1	TTL	<348..574	CDD:397308	68/264 (26%)