Protein Alignment Cnx14D and clgn

DIOPT Version :9

• Sequence 1: NP_573131.1
• Gene: Cnx14D / 32620
• FlyBaseID: FBgn0264077
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001071009.1
• Gene: clgn / 556495
• ZFINID: ZDB-GENE-060929-708
• Length: 630
• Species: Danio rerio
• Alignment Length: 666
• Identity: 306/666 - (45%)
• Similarity: 407/666 - (61%)
• Gaps: 65/666 - (9%)

  Fly     1 MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPG----------AIYGDE----KFAYKSPV 51
            :.|.  :...||||.:.......|.....|:.|:|.|          ::..|.    :..||:||
Zfish     3 LRWS--WTCFLLLSISMVTLAQDEDLEDEEEAQVEDGDLDMEADSSESVEADANVSFQVTYKTPV 65

  Fly    52 IDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKA 116
            ...:.| |.:.|||  .|...|.:|:..|.|..::||||||.|..|..:......||||||||:|
Zfish    66 PTGDVF-FTETFDD--GSLGSWQVSKTMKEDADEDIAKYDGKWEVEPLKENTVPGDLGLVLKSRA 127

  Fly   117 KHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMF 181
            ||.||:|...:||.|| :|||:||||:..|:|.||||:|:||||..|..| |.:|:|:|||:|||
Zfish   128 KHHAISALLNKPFVFK-DKPLIVQYEVNFQDGIDCGGAYIKLLSDSKDLE-LEQFHDRTPYSIMF 190

  Fly   182 GPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDH 246
            ||||||.:.|:||||||.|||||::.|||.|:|:..|...:|||..||:.||:.||||:|..:|.
Zfish   191 GPDKCGEDYKLHFIFRHKNPLNGDVEEKHAKRPDVDLKKIYTDKKTHLFTLVLNPDNSYETFIDQ 255

  Fly   247 KIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVM 311
            ..:..||||||.|||||||.|||||.|.|||.||||.|||||.|.|||:|||:|...:||.|||.
Zfish   256 SSVSRGSLLTDVVPPVNPPKEIDDPKDSKPEDWDERAKIPDPEAVKPEEWDEEALAKVPDPDAVK 320

  Fly   312 PNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWS 376
            |:|||:|||:.:.||||.:|:||:.|:|||||||.|.||.|..|||||:||.|::.||.|||||.
Zfish   321 PDGWLDDEPEFVSDPTAEKPDDWDEEMDGEWEAPQVPNPACTSAPGCGEWKPPMVNNPKYKGKWK 385

  Fly   377 APMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARD 441
            ||:|:|||.||.|:||||.|||.||||.||:|.|..|||||||||:|||.|||.|||.:.|:|..
Zfish   386 APLIDNPNYQGVWSPRKIPNPDHFEDLHPFRMEPFRAVGLELWSMTSDIYFDNFIITTEKEVADR 450

  Fly   442 FAANSFDIKRLYIDRESFG--NKVVELARANRAIWGIVIVAIAVPVA-ITIFCKFGLGPSRVAAA 503
            :||:|:.:|:|.......|  :::...|.....:|.|.|:.|.:|:. :.:||    .|.
Zfish   451 WAADSWGLKKLVASANEPGVLSQLALAAEERPWLWVIYILTIGLPIGLVVLFC----WPK----- 506

  Fly   504 KKAAAAAAKKTDDPQPDDDLGAEEEEKLE-------KGKKEEEKKEEEEEEEK--EENKEEKKEE 559
            |.......||.|.|:.:.:..|||||:.|       |||.::|.|.||..|..  :||.:...:|
Zfish   507 KSDDDYVYKKIDQPKTESEEVAEEEEEEEDEEEGDGKGKDDDEAKAEEATEATAGDENGDMMGQE 571

  Fly   560 EKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKN 624
            ..:|..|.:: ||||:|||:::..|.:|.|:.|..|                     |.::.|::
Zfish   572 NGEDGGETEE-EEEEEDEEEEEAIKPNETASEDEMK---------------------DADEGLES 614

  Fly   625 KEPTPKK-RKRKALKE 639
            :|..||. |||:..|:
Zfish   615 REEEPKAVRKRRVRKD 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx14D	NP_573131.1	Calreticulin	59..432	CDD:278680	225/372 (60%)
clgn	NP_001071009.1	Calreticulin	72..441	CDD:278680	225/372 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	518	1.000	Domainoid score	I295
eggNOG	1	0.900	-	-		E1_KOG0675
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	586	1.000	Inparanoid score	I960
OMA	1	1.010	-	-		QHG48587
OrthoDB	1	1.010	-	-		D230478at33208
OrthoFinder	1	1.000	-	-		FOG0001260
OrthoInspector	1	1.000	-	-		mtm6387
orthoMCL	1	0.900	-	-		OOG6_102144
Panther	1	1.100	-	-	O	PTHR11073
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X875
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.840