Protein Alignment Cnx14D and clgn

DIOPT Version :9

• Sequence 1: NP_573131.1
• Gene: Cnx14D / 32620
• FlyBaseID: FBgn0264077
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_002932081.3
• Gene: clgn / 100494636
• XenbaseID: XB-GENE-981033
• Length: 593
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 273/607 - (44%)
• Similarity: 371/607 - (61%)
• Gaps: 56/607 - (9%)

  Fly     3 WKMLFAILLLLSAAKTGYLAPESENS------VEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFAD 61
            |..|..:|:.|:||:..  :.:.|:|      .||.:.||......|   ||:||...:.| |.:
 Frog     6 WLCLATLLVALTAAEAH--SEQDEDSEDGLDDTEDYREEPSTFLQVE---YKTPVPMGDVF-FTE 64

  Fly    62 HFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFR 126
            .|||  .:...||||:..|.:..:|||||||.|..|..:......|:||||||.|:|.||:|..:
 Frog    65 TFDD--GTLDSWVLSKTVKEEADEEIAKYDGKWAVEELKENKVPGDMGLVLKSTARHHAISAKLK 127

  Fly   127 QPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLN--RFNDKTPYTIMFGPDKCGNN 189
            :.|.|  :|||:||||:..|:|.||||:|:||||.   ::.||  .|:|:|.|||||||||||.:
 Frog   128 KTFTF--DKPLIVQYEVNFQDGIDCGGAYIKLLSE---SDHLNLEEFHDRTSYTIMFGPDKCGED 187

  Fly   190 LKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSL 254
            .|:||||||.||:.|:..|||.|:|...|...||||..|||.|:|:|||::||.:|..::.:|||
 Frog   188 YKVHFIFRHKNPVIGDYDEKHAKRPEVDLKKYFTDKKTHLYTLIVKPDNTYEILIDQSVVGQGSL 252

  Fly   255 LTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDE 319
            ..|.:||:||..|||||.|.||:.||||.|||||||.||:||||..|..:.|.:||.|.|||::|
 Frog   253 RDDVIPPLNPLKEIDDPKDKKPKEWDERAKIPDPNAVKPDDWDEGGPEEIEDLNAVKPEGWLDNE 317

  Fly   320 PDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPN 384
            |..|.|..|.:|.|||:.:|||||||.:.|..|:.|||||.||.|:|.||:|||||..|:|||||
 Frog   318 PHFILDMNAEKPSDWNANMDGEWEAPYIPNANCESAPGCGVWKRPMIKNPDYKGKWKPPLIENPN 382

  Fly   385 NQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDI 449
            .||.|.||||.|..:||||.||:|||.:|||||||||:|||.|||.||..|.|:|..:|::|:.:
 Frog   383 YQGIWKPRKIKNSHYFEDLNPFKMTPFSAVGLELWSMTSDIYFDNFIICSDKEVADRWASDSWGL 447

  Fly   450 KRLY--IDRESFGNKVVELARANRAIWGIVIVAIAVPVA-ITIFCKFGLGPSRVAAAKKAAAAAA 511
            |:|.  .:..|..::::..|.....:|.:.|:..|:||. :.:||                 ...
 Frog   448 KKLVASANEPSMLSQLLSAAEERPWLWVLYILTAALPVGLLVLFC-----------------WPR 495

  Fly   512 KKTDDPQPDDDLGAE---EEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEE 573
            ||.::.:.|.|....   :|..||   .:...|||.:..:..||:|.::.||:.||:|....|||
 Frog   496 KKMEEEEEDFDFKLSDLCDESYLE---LQSNAKEEADGGKASENEEYERSEEEGDEEEEVSLEEE 557

  Fly   574 E---------DDEEKDDEEKTD 586
            |         |||.|:.:|.::
 Frog   558 EGAAANQSSSDDEMKESDESSE 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx14D	NP_573131.1	Calreticulin	59..432	CDD:278680	210/374 (56%)
clgn	XP_002932081.3	Calreticulin	62..430	CDD:395201	210/374 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	497	1.000	Domainoid score	I359
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	567	1.000	Inparanoid score	I1059
OMA	1	1.010	-	-		QHG48587
OrthoDB	1	1.010	-	-		D230478at33208
OrthoFinder	1	1.000	-	-		FOG0001260
OrthoInspector	1	1.000	-	-		mtm9512
Panther	1	1.100	-	-	O	PTHR11073
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X875
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080