DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Krn and Nrg2

DIOPT Version :9

Sequence 1:	NP_524129.1	Gene:	Krn / 326198	FlyBaseID:	FBgn0052179	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001129623.2	Gene:	Nrg2 / 432361	RGDID:	1303302	Length:	860	Species:	Rattus norvegicus

Alignment Length:	90	Identity:	27/90 - (30%)
Similarity:	48/90 - (53%)	Gaps:	6/90 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 YCLNDGTCFTVKIHNEILYNCECALGFMGPRCEYKEIDGSYLP----TRNRVMLEKASIVSGATL 130
            ||:|.|.|:.::..|::  :|:|..||.|.||..|.....|:|    ....:..::...::|..:
  Rat   368 YCVNGGVCYYIEGINQL--SCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICV 430

  Fly   131 ALLFMAMCCVVLYLRHEKLQKQKLH 155
            |||.:.:.|||.|.:.:|.::|..|
  Rat   431 ALLVVGIVCVVAYCKTKKQRRQMHH 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Krn	NP_524129.1	None
Nrg2	NP_001129623.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..114
		IG	259..344	CDD:214652
		EGF_CA	<369..397	CDD:238011	10/29 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	461..480
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	508..545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	663..682
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	712..798
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	815..860
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44847
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910