DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Krn and dlc

DIOPT Version :9

Sequence 1:	NP_524129.1	Gene:	Krn / 326198	FlyBaseID:	FBgn0052179	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_571019.1	Gene:	dlc / 30120	ZFINID:	ZDB-GENE-000125-4	Length:	664	Species:	Danio rerio

Alignment Length:	166	Identity:	41/166 - (24%)
Similarity:	75/166 - (45%)	Gaps:	43/166 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 CLNDGTCFTVKIHNEILYNCECALGFMGPRCEYKE----IDGSYLPTRNRVMLEKASIVSGATLA 131
            |.|.|||:| .....:   |:|..||||.:||||:    ::...||         |:::...||.
Zfish   467 CQNGGTCYT-HFSGPV---CQCPAGFMGTQCEYKQKPTPVNSPALP---------AALIVSFTLG 518

  Fly   132 L--LFMAMCCVVLYLRHEKLQKQKLHDSTTTTTTDGGCQNEGMDEVD---GLRPLRPVRR----- 186
            |  |.:.:|..::.||    |.::.|.:::||.      ...:|.|:   .|.|..|:.|
Zfish   519 LITLTLVICAAIVVLR----QMRQNHKASSTTV------RNNLDSVNNRISLSPTSPLGREKEAF 573

  Fly   187 --PFGPCRI----LSLEEAHLQAKASNRPRHCNELL 216
              |.||.::    ::|....:...:|::..:..:::
Zfish   574 LIPGGPFKVSNKDMALRSTSVDTHSSDKSNYKQKMV 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Krn	NP_524129.1	None
dlc	NP_571019.1	MNNL	21..79	CDD:284966
		DSL	136..198	CDD:279722
		EGF_CA	265..303	CDD:238011
		EGF_CA	307..341	CDD:238011
		EGF_CA	<350..380	CDD:238011
		EGF_CA	383..418	CDD:238011
		EGF_CA	420..455	CDD:238011
		EGF_CA	<466..494	CDD:238011	12/30 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910