DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Krn and zanl

DIOPT Version :9

Sequence 1:	NP_524129.1	Gene:	Krn / 326198	FlyBaseID:	FBgn0052179	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001352287.1	Gene:	zanl / 100147904	ZFINID:	ZDB-GENE-060131-2	Length:	4516	Species:	Danio rerio

Alignment Length:	93	Identity:	31/93 - (33%)
Similarity:	43/93 - (46%)	Gaps:	20/93 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 CLNDGTCFTVKIHNEILYNCECALGFMGPRCEYKEIDGSYLPTRNRVMLEKASIVSGATLA---- 131
            |.|||||...:..:.  |.|.||.||.|..||..||     |.:..  |:|.||:....|.
Zfish  4404 CQNDGTCNDKEDGSG--YTCICAEGFEGTNCELFEI-----PPKGG--LDKTSIILIGVLVPLGV 4459

  Fly   132 -LLFMAMCCVVLYLRHEKL-QKQKLHDS 157
             |:..|..|:     ::|. :|:|.:||
Zfish  4460 LLILTATVCI-----YKKCSRKKKTYDS 4482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Krn	NP_524129.1	None
zanl	NP_001352287.1	MAM	38..197	CDD:99706
		MAM	204..362	CDD:99706
		TIL	588..639	CDD:307783
		VWD	703..855	CDD:306577
		C8	892..967	CDD:214843
		TIL	970..1022	CDD:307783
		VWC	1024..1076	CDD:327433
		VWD	1083..1235	CDD:306577
		C8	1281..1349	CDD:214843
		TIL	1352..1405	CDD:307783
		VWC	1407..1460	CDD:327433
		TIL	1466..1517	CDD:307783
		VWD	1581..1733	CDD:306577
		C8	1770..1845	CDD:214843
		TIL	1848..1900	CDD:307783
		VWC	1902..1954	CDD:327433
		VWD	1961..2112	CDD:306577
		C8	2159..2227	CDD:214843
		TIL	2230..2283	CDD:307783
		VWC	2285..2338	CDD:327433
		TIL	2344..2395	CDD:307783
		VWD	2459..2611	CDD:306577
		C8	2648..2723	CDD:214843
		TIL	2726..2778	CDD:307783
		VWC	2780..2832	CDD:327433
		VWD	2839..2991	CDD:306577
		C8	3037..3105	CDD:214843
		TIL	3108..3161	CDD:307783
		VWC	3163..3216	CDD:327433
		VWD	3224..3378	CDD:306577
		C8	3422..3488	CDD:312319
		TIL	3492..3545	CDD:307783
		TILa	3547..3602	CDD:315397
		VWD	3609..3762	CDD:306577
		C8	3805..3874	CDD:214843
		TIL	3877..3932	CDD:307783
		VWC	3934..3988	CDD:327433
		VWD	3996..4150	CDD:306577
		C8	4214..4282	CDD:312319
		TIL	4286..4340	CDD:307783
		EGF_CA	4399..4433	CDD:238011	13/30 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910