DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Krn and egf

DIOPT Version :9

Sequence 1:	NP_524129.1	Gene:	Krn / 326198	FlyBaseID:	FBgn0052179	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001106478.1	Gene:	egf / 100127663	XenbaseID:	XB-GENE-951823	Length:	1051	Species:	Xenopus tropicalis

Alignment Length:	116	Identity:	31/116 - (26%)
Similarity:	51/116 - (43%)	Gaps:	11/116 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 CPPTYVAWYCLNDGTCFTVKIHNEIL--YNCECALGFMGPRCEYKEIDGSYLPTRNRVMLEKASI 124
            ||..|.. ||||.|.|    ||...|  |.|.|..|::|.||::.::. |:.....::.:...:|
Frog   930 CPLAYDG-YCLNGGVC----IHFPELKDYGCRCVAGYVGERCQFDDLK-SWEKHVTQMKIHNVTI 988

  Fly   125 VSGATLALLFMAMCCVVLYLRHEKLQKQKLH---DSTTTTTTDGGCQNEGM 172
            .....|.||.:.:....:|....::..:|.|   ::...||....|...|:
Frog   989 AVSLLLLLLILGLGSFAIYYYRHQMTHRKNHFKQETAPGTTEKPICSTSGL 1039

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Krn	NP_524129.1	None
egf	NP_001106478.1	LY	152..194	CDD:214531
		vWFA	<346..398	CDD:320736
		FXa_inhibition	412..440	CDD:317114
		FXa_inhibition	447..480	CDD:317114
		LY	508..550	CDD:214531
		LY	554..593	CDD:214531
		Ldl_recept_b	615..654	CDD:278487
		LY	638..680	CDD:214531
		EGF_3	810..838	CDD:315598
		EGF_3	851..880	CDD:315598
		EGF_3	886..>914	CDD:315598
		PHA02887	<927..>967	CDD:333467	18/41 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910