DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndfip and Ndfip2

DIOPT Version :9

Sequence 1:	NP_730291.1	Gene:	Ndfip / 326197	FlyBaseID:	FBgn0052177	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001177918.1	Gene:	Ndfip2 / 76273	MGIID:	1923523	Length:	338	Species:	Mus musculus

Alignment Length:	227	Identity:	72/227 - (31%)
Similarity:	108/227 - (47%)	Gaps:	36/227 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 VQLPSQADLMNAQLPPEIHGKLPTYEEVQMEKSLNGELPPAFLTL----PS-------SQQLP-P 114
            |:.||.:.|           ..||.|......:|:.:.||.:.::    |:       |:..| |
Mouse   123 VEQPSTSSL-----------AAPTVEAAASAPALDPDSPPPYSSITVEAPTTSDTDVYSEFYPVP 176

  Fly   115 PPNPLLPPNPLRDGAAAVRSAQPALTFIAIDASD--------PENSLSTTDNL-LGTDIMFITAF 170
            ||..:....|..|.|...::|  ||...|.||..        |.:..|..:.| :|.|.:|:.||
Mouse   177 PPYSVATSLPTYDEAEKAKAA--ALAAAAADAPQRNQEEDCTPRDDFSDVEQLRVGNDGIFMLAF 239

  Fly   171 IVAFLFNWIGFLMLTCFCHTIAARYGALSGFGLSLAKWTLIVKHSTDLASHENS--WLWWLICAF 233
            .:||:|||:||.:..|..:|||.||||:.||||||.||.|||:.|.....:.|.  ||||:....
Mouse   240 FMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVL 304

  Fly   234 GFLISIRALIQYVSIKRSWRLLSASAQERLLF 265
            |.|:..|..:.|:.::.....::|:.:.|..|
Mouse   305 GLLLFFRGFVNYLKVRNMSESMAAAHRTRYFF 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndfip	NP_730291.1	None
Ndfip2	NP_001177918.1	ABC2_membrane	<233..300	CDD:304374	34/66 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4812
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I4877
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002313
OrthoInspector	1	1.000	-	-		otm44152
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13396
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5682
SonicParanoid	1	1.000	-	-		X2006
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.920