Protein Alignment CG32086 and Efhb

DIOPT Version :9

• Sequence 1: NP_729720.1
• Gene: CG32086 / 326195
• FlyBaseID: FBgn0052086
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_766085.2
• Gene: Efhb / 211482
• MGIID: 3045296
• Length: 853
• Species: Mus musculus
• Alignment Length: 615
• Identity: 139/615 - (22%)
• Similarity: 223/615 - (36%)
• Gaps: 196/615 - (31%)

  Fly     5 GHFIDRNANIPTAG-LSTSGLDGAEGVKVCLS-----ISNPEELAE---------SLVRRNYGQI 54
            |.|.||....|:|| :...|.    .|..||:     :..|.|..:         ...|..||:.
Mouse   272 GKFFDRVPCWPSAGKVKPVGY----RVATCLTEKLPRLMTPPEAKKYFNFRYPPAGAERVFYGRA 332

  Fly    55 N------------KKSQKFPAGSV---QPSSSIRDLLTSELQKSRFMSFKEKFYEEMYF--KKAT 102
            |            :.....|.||:   ||       :|:..||     .|:| .|.:||  ::|.
Mouse   333 NDPQIAPYLTHGLRSKISIPMGSLINPQP-------ITTFQQK-----IKDK-KESIYFSHQRAP 384

  Fly   103 LG-GVKKTYSKPEDVTNISQTFGSPSSQSQNECLYDVILPAKSAEQVNKEYEAFHDKYIISHNHY 166
            || ...:|...|:.:..|:.|.|:|:.:..:  :.|.:.|:||.|.|.||.:..||.|.:|||.|
Mouse   385 LGKSHDQTPGLPKGMDVINTTLGTPTIRELS--VRDTVNPSKSFEDVLKEGQEGHDLYTVSHNDY 447

  Fly   167 FPSEQVNRRY-AQPFDRKSPCGDIHTHGDFGLKVKRCLE-----EGENHLKVIGKAQVDFMDRNE 225
            |..|..||:| ...|.|.:..|....|.:.|..:.:.|.     :.|...|::.|...||.::.:
Mouse   448 FAGEAKNRKYNPASFHRFNLYGIPTPHFNDGRTMAKALHWLHELQMERGAKIVSKRVDDFKEKFQ 512

  Fly   226 APLG--MRNKKYTFAV-PDITFGVPLRSN----GDVKMLLNNIEPCYKTNRLLDAIRYLNKK--- 280
            ..||  :.....|..| |..|||..|...    ||   |::...|          ..||..|
Mouse   513 HKLGKVLDPIAETMNVPPGHTFGSCLHPEEYGAGD---LIHYRSP----------DEYLRGKDHQ 564

  Fly   281 -------RHSLRN---------QLEFHKYALNSVLERSDTDGTGHLPLARILEIFRSFHIRLDAQ 329
                   ||.|:.         |:.|..|         |..|.|.:..|.:.|.....::.||
Mouse   565 RAVVAAARHHLKKFNHQNFDTLQVAFRHY---------DKKGDGVIDRAELHEACVQANLHLD-- 618

  Fly   330 KIRLALSNFRLIVD---EGCATER---VNYVDFFRLLSIQNSLP------------KTGNLTNVS 376
                     ::::|   :.|..::   :||::|...|:.::.:|            |..:..||:
Mouse   619 ---------KMLLDHLFDYCDVDQDGLINYLEFANFLNWKDRIPLKEHEKRVVVKGKKPDCENVT 674

  Fly   377 DVSCLDTTYRLLC--ADLQNK---SKDNT--------------------------GAI------- 403
            |.|..:....||.  .|:..|   |.:.|                          ||:
Mouse   675 DTSMGEAEPSLLINPEDIVPKEPGSSEETLRTIQRPGDKVSHQYKTTSSEINAVVGAVPSMCHPI 739

  Fly   404 -------------------SQNLEGNKTTAKDLITPDLAILRGLTHSDFTCLRPKAEIERIFRSL 449
                               ..|..|::..|..|:.|.:...:|:...||...|.|.||..|..::
Mouse   740 FGVPTIRSDISAPRIRRVSDMNNYGDEGNAYSLLHPSIFSQKGVFERDFFKTRSKEEISDILTNI 804

  Fly   450 ---VTTDKFEAIWQSLMTKFKDQNEMASVT 476
               ::.::||.:| :|.:|...:.|:...|
Mouse   805 GVKLSKEEFENVW-NLASKKHQRGEVCVET 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32086	NP_729720.1	None
Efhb	NP_766085.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..266
		EF-hand_7	586..646	CDD:290234	15/79 (19%)
		EFh	586..646	CDD:238008	15/79 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CJU2
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I5054
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42829
orthoMCL	1	0.900	-	-		OOG6_104929
Panther	1	1.100	-	-	LDO	PTHR12086
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5195
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.940