DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32081 and polyph

DIOPT Version :9

Sequence 1:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	174/423 - (41%)
Similarity:	271/423 - (64%)	Gaps:	3/423 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FDPYENRNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLI 71
            ::|||.|:|..|:::..||.||||||:|||::|:||:|..:|.|.|.::.:.:..:|.:.:.:||
  Fly    34 YNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLI 98

  Fly    72 ICMIECSRRMQIGYATYPVAMVYSFDQGPRFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAAT 136
            ..|.||.||.::...:.|.|:..::::||::.....:|..::...||.|.||.:|.||.|||:..
  Fly    99 ADMTECCRRRRVPQVSMPEAVRIAYEEGPKWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKN 163

  Fly   137 LKQLVDFYWVVADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYLFVDLPP 201
            .|::.|.|....:.|.|:.|..|.|:|.|.||:||||||.|::::.|:|.||:|:|||||..||.
  Fly   164 FKEIGDHYIERYNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPN 228

  Fly   202 ITERNILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTF 266
            |.:|.::...::.|. |..||.||:|:||.||.|||.||.|:.|||.||:|:.|:|.:::|.:.|
  Fly   229 INDREMVTPPVEWIE-FIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFF 292

  Fly   267 GLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKNGDLP 331
            |::||||:||....||:||||.||:|||..|.|||:.|||:|||.|||:|.::.:.:.|......
  Fly   293 GIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEPRGR 357

  Fly   332 NAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPPEYNYGKL 396
            ...|.|.::|...:.|....||..|||..|..|.||.::|.|||:.||||::.|.|  ...||:|
  Fly   358 YRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNY--NVGYGRL 420

  Fly   397 KWVLVKDIFYVIVGILILVQGTVFSIKDMISEW 429
            .|.|::||..:::|::..:.|...::..:|.::
  Fly   421 MWKLIRDILLILIGLIFGIVGCTVALMQLIRDF 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	168/404 (42%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	166/394 (42%)
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	154/357 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466548
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.990