DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32081 and Slc36a4

DIOPT Version :9

Sequence 1:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_001101597.1	Gene:	Slc36a4 / 315439	RGDID:	1311528	Length:	500	Species:	Rattus norvegicus

Alignment Length:	476	Identity:	133/476 - (27%)
Similarity:	232/476 - (48%)	Gaps:	66/476 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 HPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICM-IECSR- 79
            |.||.:.....|||..:|||::.:||:...||||.|.|.||.:..:.:|.|.:|:.|. ..|.|
  Rat    54 HGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRF 118

  Fly    80 -RMQIGYATYPVAMVYSFDQGPRFFKYISKA---GRYIVDGVLAFSQFGVCVVYNVFVAATLKQ- 139
             :..:||:.   .:.::.:..|  :..:.:.   ||.:||..|..:|.|.|.||.||:|..:||
  Rat   119 KKSTLGYSD---TVSFAMEASP--WSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQV 178

  Fly   140 ---LVDFYWVVA--------------DLRIYIAVIALCLIPPF----QIRKLKYLVPFNILASIL 183
               |::...||:              |||:|:    ||.:|..    .||:||.|...:.||:|.
  Rat   179 HEGLLETTVVVSNSSDLSQVCERRSVDLRVYM----LCFLPLLILLVFIRELKSLFVLSFLANIS 239

  Fly   184 IYTGFSLMMYYLFVDLPPITERNILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGW 248
            :.....::..|:...:|......|:.| ..|.|||||.|:|:...:||:|.:|..|.:.:.:.
  Rat   240 MAASLVIIYQYVVRSMPDPHNLPIVAG-WKKYPLFFGTAVFAFEGIGVVLPLENQMRESKRFP-- 301

  Fly   249 FGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGF 313
             ..|:..:.:|.:.|::...:||..:.||..|||:||:|.|..|.|..|...:..||:||.:..:
  Rat   302 -QALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLPQDMWLYQSVKILYSFGIFVTYSIQFY 365

  Fly   314 VIIDII-------MNHFWNKNGDLPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTIS 371
            |..:||       ::..|.        .:.:..:|:..|.:.|..|::.|.|..::|.|||::.|
  Rat   366 VPAEIIIPAVTARLHAKWK--------CICDFGIRSLLVSITCAGAVLIPRLDIVISFVGAVSSS 422

  Fly   372 LLNLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISEWGGGDTTT 436
            .|.|:.|.|:||..:....||.    |:::|:|.....|.:..:.||..:::::|.      .||
  Rat   423 TLALILPPLVEILTFSKDHYNV----WMVLKNISIAFTGFVGFLLGTYVTVEEIIY------PTT 477

  Fly   437 GGPETTAEETTANMSATLTTA 457
            ...:..::..:.|:::|..::
  Rat   478 AVADGASQSLSLNVNSTCVSS 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	128/439 (29%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	124/429 (29%)
Slc36a4	NP_001101597.1	SLC5-6-like_sbd	54..469	CDD:294310	128/439 (29%)
Slc36a4	NP_001101597.1	PotE	<223..477	CDD:223605	76/275 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352600
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940