DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32081 and Slc38a3

DIOPT Version :9

Sequence 1:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_665719.1	Gene:	Slc38a3 / 252919	RGDID:	628620	Length:	504	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	90/486 - (18%)
Similarity:	174/486 - (35%)	Gaps:	128/486 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIIC--MIECSRRMQIGYATY 88
            |:|...::|:|::.:..:....||:..:.||.:|..:..:.:.:|:..  ::......|:||..:
  Rat    72 FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAF 136

  Fly    89 PVAMVYSFDQGPRFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDFY--------- 144
                              ...|:......:.....|....|...:.:.|..::..:
  Rat   137 ------------------GTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPTPV 183

  Fly   145 WVVADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSL--MMYYL------------ 195
            |.:....:.|.|..:.::|...:|:|.||.         ..:||||  |:::|
  Rat   184 WYMDGNYLVILVSVIIILPLALMRQLGYLG---------YSSGFSLSCMVFFLIAVIYKKFQVPC 239

  Fly   196 ------------FVDLPPITERNILFGRIDKIPLFFGIALFSITS-----VGVM----------L 233
                        |..:..:.|::.|....|....|...:.|::.|     :.:|          |
  Rat   240 PLAHNLVNATGNFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVL 304

  Fly   234 AVEATMAKP-----RHYLGWFGILDRAILLVIISYVTFGLMGYWRYGD----ETAGSISLNIPTD 289
            .:...:..|     :|      |.:.:|.::.:.|....|.||..:.|    |...:.|...|.|
  Rat   305 PIYTELKDPSKRKMQH------ISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFD 363

  Fly   290 EVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKNGDLPNAALKESILR---ACTVVLICIT 351
             ||....:..:..|:.||.|:..|.:...|....:...        :.|.||   ..|.:|.||.
  Rat   364 -VLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQ--------EFSWLRHVLIATGLLTCIN 419

  Fly   352 --AIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYY-------PPEYNYGKLKWVLVKDIFYV 407
              .|.|||:..:..::||.:...|..:|||:    .|:       .|..:..|     :..:.:.
  Rat   420 LLVIFAPNILGIFGIIGATSAPCLIFIFPAI----FYFRIMPTEKEPVRSTPK-----ILALCFA 475

  Fly   408 IVGILILVQGTVFSIKDMISEWGGGDTTTGG 438
            .||.|::    ..|:..:|::|..|.:..||
  Rat   476 AVGFLLM----TMSLSFIITDWVSGTSQHGG 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	84/468 (18%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	84/461 (18%)
Slc38a3	NP_665719.1	Aa_trans	63..491	CDD:279788	85/473 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830