DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32081 and Slc38a4

DIOPT Version :9

Sequence 1:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_570104.1	Gene:	Slc38a4 / 170573	RGDID:	621836	Length:	547	Species:	Rattus norvegicus

Alignment Length:	509	Identity:	89/509 - (17%)
Similarity:	176/509 - (34%)	Gaps:	158/509 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRMQIGYATYPV 90
            |:|...::|:|::.:..:....|||..:|:|::|..:.::.:.:|:....|..
  Rat    82 FNLSNAIMGSGILGLSYAMANTGIVLFVIMLLTVAILSLYSVHLLLKTAKEGG------------ 134

  Fly    91 AMVYSFDQGPRFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDFY---------WV 146
            :::|. ..|.:.|.:..|.|.:|   .:.....|....|...:...|.:::..:         |.
  Rat   135 SLIYE-KLGEKAFGWPGKIGAFI---SITMQNIGAMSSYLFIIKYELPEVIRVFMGLEENTGEWY 195

  Fly   147 VADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYT-GFSLMMYYLFV--------DLP-- 200
            :....:.:.|....::|...::.|.||.          || ||||.....||        .:|
  Rat   196 LNGNYLVLFVSVGIILPLSLLKNLGYLG----------YTSGFSLTCMVFFVSVVIYKKFQIPCP 250

  Fly   201 -PITER---NILFGRIDKIPLFFGIALFSITSVGVMLAVEAT-----------MAKPRHYLG--- 247
             |:.:.   |:.|.  :.:|:...:...:..|.|:...|:.|           .|.|.|..|
  Rat   251 LPVLDHNNGNLTFN--NTLPMHVIMLPNNSESTGMNFMVDYTHRDPEGLDEKPAAGPLHGSGVEY 313

  Fly   248 ---------------------------------------WFGILDR-----------AILLVIIS 262
                                                   :..:.||           :|..:::.
  Rat   314 EAHSGDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVM 378

  Fly   263 YVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGF------------IAAAIFLTYPLAGFVI 315
            |:...|.||..:..|.         .||:|...:|.:            :..|:.||.|:..|.|
  Rat   379 YLLAALFGYLSFYGEV---------EDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLFPI 434

  Fly   316 IDIIMNHFWNKNGDLPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPAL 380
            ...::...:.:.   |.:.:|...:.|..:.|..:..|:.|.:..:...:||.:.::|..:.||
  Rat   435 RTSVITLLFPRR---PFSWVKHFGIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPA- 495

  Fly   381 IEICLYYPPEYNYGKLKWVLVKDIF--YVIVGILILVQGTVFSIKDM---ISEW 429
                .:|        ||.|..:.:.  ..|..::.||.|.:|.:..|   |.:|
  Rat   496 ----AFY--------LKLVKKEPLRSPQKIGALVFLVTGIIFMMGSMALIIIDW 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	86/497 (17%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	82/490 (17%)
Slc38a4	NP_570104.1	SLC5-6-like_sbd	73..535	CDD:382020	87/505 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830