DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32081 and SLC36A2

DIOPT Version :9

Sequence 1:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_861441.2	Gene:	SLC36A2 / 153201	HGNCID:	18762	Length:	483	Species:	Homo sapiens

Alignment Length:	428	Identity:	125/428 - (29%)
Similarity:	206/428 - (48%)	Gaps:	44/428 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 AFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRMQIGYATY 88
            |...|:|..:|||::.:||:...|||:.|.:.|:.:.|:..|.|.:|:.|.....:|:...:..|
Human    59 ALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPFMDY 123

  Fly    89 PVAMVYSFDQGPR-FFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVD---------- 142
            ...:::..:..|. :.:..:..||:||...|..:|.|.|.||.||:|..|||:|:
Human   124 GDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCY 188

  Fly   143 -----FYWVVADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYLFVDLPPI 202
                 ......|.|:|:......|:....||.|:.|..|::||:|.:.....:::.|:..::|.
Human   189 SNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYITQEIPD- 252

  Fly   203 TERNILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFG 267
            ..|..|.......|||||.|:||..|:||:|.:|..|...||:.   .||...:.:|...|:...
Human   253 PSRLPLVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFP---AILSLGMSIVTSLYIGMA 314

  Fly   268 LMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKNGDLPN 332
            .:||.|:||:...|||||:| :..|.|..|....|.|..||.|..:|..:||          :|.
Human   315 ALGYLRFGDDIKASISLNLP-NCWLYQSVKLLYIAGILCTYALQFYVPAEII----------IPF 368

  Fly   333 AALKESI---------LRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYP 388
            |..:.|.         :|...|.|.|:.||:.|.|..::||||:::.:.|.|:.|.|:|:..:
Human   369 AISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTF-- 431

  Fly   389 PEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMI 426
              |:.|.....:.||....|:|.:..|.||..::.:::
Human   432 --YSEGMSPLTIFKDALISILGFVGFVVGTYQALDELL 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	125/422 (30%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	122/415 (29%)
SLC36A2	NP_861441.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..46
SLC36A2	NP_861441.2	SLC5-6-like_sbd	52..463	CDD:320982	125/422 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940