DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32081 and slc36a4

DIOPT Version :9

Sequence 1:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	XP_002940192.3	Gene:	slc36a4 / 100493349	XenbaseID:	XB-GENE-994062	Length:	523	Species:	Xenopus tropicalis

Alignment Length:	460	Identity:	142/460 - (30%)
Similarity:	222/460 - (48%)	Gaps:	59/460 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DKGGF---DPYENRNVAHPISDIGAFFS----LLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVC 60
            |..||   ..|..|.......|...||.    |||..:|||::.:||:...||::.|.|.|:...
Frog    63 DSDGFGDEHQYLQRRQHSDSKDGLTFFQTLIHLLKGNIGTGLLGLPLAIKNAGLLLGPISLLFFG 127

  Fly    61 FMLIHGMQMLIICM-IECSR--RMQIGYA-TYPVAMVYSFDQGPR-FFKYISKAGRYIVDGVLAF 120
            .:.||.|.:|:.|. ..|.|  :..:||: |..:|:    :.||. |.:..:..||.:||..|..
Frog   128 IISIHCMNILVRCSHFLCQRYKKANLGYSETVGLAL----EVGPSGFLQRRASFGRSMVDWFLVV 188

  Fly   121 SQFGVCVVYNVFVAATLKQLVDFY-------------WVVADLRIYIAVIALCLIPPFQIRKLKY 172
            :|.|.|.||.||:|..:||:::.:             |.: |||||:......:||...||.||.
Frog   189 TQLGFCSVYFVFLAENIKQVLEVFLATKLQQPGIGGIWTL-DLRIYMFSFLPLIIPLVFIRDLKN 252

  Fly   173 LVPFNILASILIYTGFSLMMYYLFVDLPPITERNILFGRIDK-IPLFFGIALFSITSVGVMLAVE 236
            |...:.||::.:  ..||::.|.:|.......|.:..|...| .|||||.|:|:...:||:|.:|
Frog   253 LSLLSFLANLSM--AISLIIVYQYVIRNLSDPRALPLGTSWKTYPLFFGTAIFAFEGIGVVLPLE 315

  Fly   237 ATMAKPRHYLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIA 301
            ..|...:.:   ...|:..:.:|...|::...:||:.:||:..|||:||:|.|..|.||.|...:
Frog   316 NRMRDKKDF---SKALNIGMAIVTALYISLATLGYFCFGDQIKGSITLNLPQDSWLYQVVKILYS 377

  Fly   302 AAIFLTYPLAGFVIIDIIMNHFWNKNGDLP---------NAALKESILRACTVVLICITAIIAPN 357
            ..|::||.:..:|..:||          ||         ...|.|..:|...|.|.|..|::.|.
Frog   378 FGIYVTYAIQYYVPAEII----------LPAVTSRVQKTRKLLCEFTMRFFLVCLTCAFAVLIPR 432

  Fly   358 LGPLLSLVGALTISLLNLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSI 422
            |..::|.|||::.|.|.|:.|.|:||..:.....:    .||:.|||....:|.:..:.||..:|
Frog   433 LDLVISFVGAVSSSTLALILPPLVEIITFQKEHLS----PWVIAKDIAIAAIGFVGFLAGTYVTI 493

  Fly   423 KDMIS 427
            ::|||
Frog   494 EEMIS 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	133/436 (31%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	131/426 (31%)
slc36a4	XP_002940192.3	SLC5-6-like_sbd	84..493	CDD:382020	133/432 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110