Protein Alignment CG32075 and Las1l

DIOPT Version :9

• Sequence 1: NP_001246712.1
• Gene: CG32075 / 326192
• FlyBaseID: FBgn0052075
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001361646.1
• Gene: Las1l / 76130
• MGIID: 1923380
• Length: 776
• Species: Mus musculus
• Alignment Length: 602
• Identity: 128/602 - (21%)
• Similarity: 222/602 - (36%)
• Gaps: 142/602 - (23%)

  Fly    32 PPNVKQRTVVTPWRDTLEFNTTYKWLFGKSNTPATWRQALSKIRIWCLRRGSLCPAAVLATSVLV 96
            |.:...|.:|..|....|:.....:||  .:.....:.||::|.:|..|.|:..|.||.:|:.||
Mouse    18 PESPSARGIVVSWLSRAEWEQVTVYLF--CDDHKLQQYALNRITVWRSRLGNELPLAVASTADLV 80

  Fly    97 QAHLEDQEGSA---KIQDTYASAFTRFYNFMSS-IIQGHNMSSMYETAKELGLQSFIVDLRHLCA 157
            :..|.|..|:.   :::..|..|..||.|.:|. ..:..|:...| .|:|:.:..:||:|||...
Mouse    81 RCKLIDAAGTLGTDELRLLYGMALVRFVNLISERKTKCSNLPLKY-LAQEVNIPDWIVELRHNLT 144

  Fly   158 HGQELPPVEVLRNTSNHCLEWLRTYYWLPHME----TMSNLDAGKLHRKDKLKFEKAV--TDLLE 216
            | :::|.:...|......|.||:..||...:|    ....||..:|..:|..:.|:.:  .|:||
Mouse   145 H-KKMPHINECRRGCYFVLNWLQKTYWSRQLEGSLKETWELDEDQLDAEDPEEEEREIIADDVLE 208

  Fly   217 IY----------DLTLE--CHIKGAEKLKAISKLKSSGE--FNKIRVYSSS------KKAKTSKE 261
            ..          :|.:|  .:.||.|::.:..:..|..:  :.|.|....|      |..:..:.
Mouse   209 EIPEPQDDDKDEELAVEDDANTKGNEEVASHPEPSSRHKELYEKARELLVSYEEEQFKVLEKHRH 273

  Fly   262 ILSA--VLGDLSALVKKESSSMKDL--------LDIYTK---CLLKMKYFLGVGLEIDDNE---- 309
            :|.|  |..:||..|:.....:|.:        ||.:..   .:...:....:.:|.:|.:
Mouse   274 LLQAIKVWNNLSPRVQCILEELKSISWENRDAVLDAFLDDGFLIPTFEQLAALQIEYEDGQTEVQ 338

  Fly   310 ----------------DVII---------AATQGLFRLLAVQGYIEKVFLAL------------- 336
                            :|::         ...:||......|..:|::|..|
Mouse   339 KGEVTEPNSHKNIDLNEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTVGSTGIRPTYI 403

  Fly   337 ----VQL--SENQNESEQRRLGASYW-AKKMLETFGMLFRMKRMYKAELDLNDKLK-----PADF 389
                |:|  :..:.....||..||.| |:|....|..        .|.||....::     |...
Mouse   404 LRWTVELIVANTKTGRNARRFSASQWEARKSWRLFNC--------SATLDWPQVIESCLGSPCWA 460

  Fly   390 ATLNTDKISKTMRSLLVHSNAD--LSVTLIFGDNPKKSRSLIFDRDFIMQRVDAFSNYS---AP- 448
            :......:.|.|..:|.....:  |.|..|:..|.:..         :.:.::..|:.|   ||
Mouse   461 SPQLLQVVFKAMGQVLPDEEQEKLLRVCSIYTQNGENG---------LAKAIEGSSSSSTGKAPY 516

  Fly   449 ILKGLLPLADPPYTKTQIEDLTK------LCDAQL-------EEFYEEEAMEEDSSSEESNNLDR 500
            .|..|.....||.|..:.|:..:      |.|.:.       ||..|||.|||:...||....:.
Mouse   517 TLDTLHEDLQPPGTNCESEESIQQKEQGNLKDVKQEEKKENEEEEKEEEEMEEEEEEEEEEKEEE 581

  Fly   501 LERFLEQAAQSKEHTSD 517
                 |:..:.:||..:
Mouse   582 -----EEEQEQEEHQEE 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32075	NP_001246712.1	Las1	42..186	CDD:281960	42/147 (29%)
Las1l	NP_001361646.1	Las1	28..172	CDD:367775	42/147 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	185..247		13/61 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	501..646		25/98 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	733..759

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848762
Domainoid	1	1.000	57	1.000	Domainoid score	I10884
eggNOG	1	0.900	-	-		E1_KOG2425
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005077
OrthoInspector	1	1.000	-	-		oto92537
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15002
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R650
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.960