Protein Alignment para and Catsper4

DIOPT Version :10

• Sequence 1: NP_001259619.1
• Gene: para / 32619
• FlyBaseID: FBgn0285944
• Length: 2145
• Species: Drosophila melanogaster
• Sequence 2: NP_808534.1
• Gene: Catsper4 / 329954
• MGIID: 3043288
• Length: 442
• Species: Mus musculus
• Alignment Length: 293
• Identity: 74/293 - (25%)
• Similarity: 131/293 - (44%)
• Gaps: 52/293 - (17%)

  Fly  1296 QLIENKYFETAVITMILMSSLALALE-DVHLPQRPILQDILYYMDRIFTVIFFLEMLIKWLALGF 1359
            ||:.:..|:..:..::|.:::.:||. :.:|.|:.  .::...:|.|...|...|:|:.||. ||
Mouse    63 QLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKH--YELFSTIDDIVLTILICEVLLGWLN-GF 124

  Fly  1360 KVYFTNAWCWLDFVIVMVSLINFVASLVGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALV 1424
            .:::.:.|..|:|.||.:..:.|....:....|     ...||.||.:.....::.:..::..::
Mouse   125 WIFWKDGWNILNFAIVFILFMGFFIKQLDMVAI-----TYPLRVLRLVHVCMAVEPLARIIKVIL 184

  Fly  1425 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCEDMNGTKLSHEIIPNRNACESENYTWVNSA 1489
            |::|.:.||:.:.|.|.|:|::.||.||..                .:|.
Mouse   185 QSMPDLANVMALILFFMLVFSVFGVTLFGA----------------FVPK--------------- 218

  Fly  1490 MNFDHVGNAYLCLFQVATFKGWIQIMND-AIDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTLN 1553
             :|.::|.|...||...|..||:.|..| .:|.||...:      :...:||..||..|:|..||
Mouse   219 -HFQNMGVALYTLFICITQDGWLDIYTDFQMDEREYAME------VGGAIYFAVFITLGAFIGLN 276

  Fly  1554 LFIGVIIDNFNEQKKKAG---GSLEMFMTEDQK 1583
            ||:.|:..|. ||..|.|   |.|.:..||.::
Mouse   277 LFVVVVTTNL-EQMMKTGEEEGHLNIKFTETEE 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
para	NP_001259619.1	Ion_trans	152..436	CDD:459842
		Na_trans_cytopl	555..740	CDD:463401
		Ion_trans	817..1028	CDD:459842
		Na_trans_assoc	1054..1296	CDD:461936	74/293 (25%)
		Ion_trans	1300..1571	CDD:459842	67/272 (25%)
		Na_channel_gate	1561..1613	CDD:240441	9/26 (35%)
		Ion_trans	1621..1871	CDD:459842
		GPHH	1882..1929	CDD:465306
Catsper4	NP_808534.1	Ion_trans	81..289	CDD:459842	63/254 (25%)