DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment S-Lap4 and LAP2

DIOPT Version :9

Sequence 1:	NP_729613.1	Gene:	S-Lap4 / 326188	FlyBaseID:	FBgn0052064	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_194821.1	Gene:	LAP2 / 829216	AraportID:	AT4G30920	Length:	583	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	130/514 - (25%)
Similarity:	228/514 - (44%)	Gaps:	63/514 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KG--LVVGVYQKE--NDNDPKL-TPAGEKVNDRLHGKLQEMICQSKITGHLGRGKIFNNIDPEFR 95
            ||  |.|||.:|:  .|.:.|. .|..:|::..|.|.|.::..:...:|..|:..:.     ...
plant    92 KGDILAVGVTEKDMAKDVNSKFENPILKKLDAHLGGLLADVSSEEDFSGKPGQSTVL-----RLP 151

  Fly    96 SMAVVGVGLEGIGFNELEMLDEGMENVRVAAGIGARSLQEIGVSEVFVDGMDYAEQA-------- 152
            .:....|||.|:|  :........:::..|....|::.|...|:.|.......:.::
plant   152 GLGSKRVGLIGLG--KSASTPSAFQSLGEAVAAAAKASQASSVAVVLASSESVSNESKLCSASAI 214

  Fly   153 AEGAVLAVWRYCDMNSKRKPPHIPKLELY---ESPDYEGWTR-------GVFKAEAQNLARRMCD 207
            |.|.||.::......|:.|.|.:..:::.   ..|:.|...:       ||.      ..:.:.:
plant   215 ASGTVLGLFEDSRYKSESKKPSLKSVDIIGFGSGPELEKKLKYAEHVSYGVI------FGKELVN 273

  Fly   208 TPACCMTPTLFAQATVD--ALCPCGITVEIRTMEWIEQQRLHSFLMIAKGSCEPPVLMEITYCGT 270
            :||..:||.:.|:..::  ::....:|..|...|..::.::.|:|.:|..|..||..:.:.|
plant   274 SPANVLTPAVLAEEALNLASMYSDVMTANILNEEQCKELKMGSYLAVAAASANPPHFIHLIY--- 335

  Fly   271 NPEDKPI----LFLGKGITFNSGAMNLRKCRG--MEEYRACMSGAASCVAMMRCVAALALP-INV 328
            .|...|:    ..:|||:||:||..|::...|  :|..:..|.|:|:.:...:.:..:..| :.|
plant   336 KPSSGPVKTKLALVGKGLTFDSGGYNIKTGPGCLIELMKFDMGGSAAVLGAAKAIGQIKPPGVEV 400

  Fly   329 CCIIPLCENMPSGMACKPGDVVTLMNHKSMAVRNLDKAGVVVMADPLLY--GQSTYKPRLVVDVA 391
            ..|:..||||.||...:||||:|..|.|::.|.|.|..|.:.:||.|:|  .|...|   |||:|
plant   401 HFIVAACENMISGTGMRPGDVLTASNGKTIEVNNTDAEGRLTLADALVYACNQGVDK---VVDLA 462

  Fly   392 TLGSGVKKAFGGGATGIFSNSHYIWKQFQSAGALTGDRVWRLPLWNYYRKQITDEMGYDLSNDGR 456
            ||......|.|....||::.|..:.|:..:|...:|:::||:|:...|.:.:...:. |:.|.|.
plant   463 TLTGACIIALGTSMAGIYTPSDKLAKEVIAASERSGEKLWRMPMEESYWEMMKSGVA-DMVNTGG 526

  Fly   457 GLANSCLAAAVLHELV-PCVDWAHLDTRGTGLLTKYGLVPYLTAKYMTGRPTRTLAQFL 514
            ....|..||..|.:.| ..|:|.|:|..|.....|        .|..||....||.:::
plant   527 RAGGSITAALFLKQFVSEDVEWMHIDMAGPVWNEK--------KKAATGFGVATLVEWV 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap4	NP_729613.1	PRK00913	31..514	CDD:234863	130/512 (25%)
S-Lap4	NP_729613.1	Peptidase_M17	35..514	CDD:238247	130/512 (25%)
LAP2	NP_194821.1	PRK00913	81..579	CDD:234863	130/514 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1254
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1544
OMA	1	1.010	-	-		QHG61256
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	1	1.000	-	-		FOG0001058
OrthoInspector	1	1.000	-	-		mtm1057
orthoMCL	1	0.900	-	-		OOG6_100682
Panther	1	1.100	-	-	O	PTHR11963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X713
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840