DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment S-Lap4 and AT4G30910

DIOPT Version :9

Sequence 1:	NP_729613.1	Gene:	S-Lap4 / 326188	FlyBaseID:	FBgn0052064	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001328632.1	Gene:	AT4G30910 / 829215	AraportID:	AT4G30910	Length:	604	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	131/542 - (24%)
Similarity:	227/542 - (41%)	Gaps:	96/542 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KG--LVVGVYQKE--NDNDPKL-TPAGEKVNDRLHGKLQEMICQSKITGHLGRGKIFNNIDPEFR 95
            ||  |.|||.:|:  .|.:.|. .|..:|::..|.|.|.::..:...:|..|:..:........:
plant    91 KGDILAVGVTEKDMAKDANSKFENPILKKLDAHLGGLLADVSAEEDFSGKPGQSTVLRLPGLGSK 155

  Fly    96 SMAVVGVGLEGIGFNELEMLDEGMENVRVAAGIGARSLQEIGV----SEVFVD--GMDYAEQAAE 154
            .:.::|:|......:..:.|.|.     |||...|.....:.|    ||.|.|  .:..|...|.
plant   156 RVGLIGLGKSASTPSAFQSLGEA-----VAAAAKASQASSVAVVLASSESFSDESKLSSASDIAS 215

  Fly   155 GAVLAVWRYCDMNSKRKPPHIP---------------KLELYESPDYEGWTRGVFKAEAQNLARR 204
            |.||.::......|:.|.|.:.               ||:..|...|     ||.      ..:.
plant   216 GTVLGLFEDSRYKSESKKPSLKSVVFIGFGTGPELENKLKYAEHVSY-----GVI------FTKE 269

  Fly   205 MCDTPACCMTPTLFAQ--ATVDALCPCGITVEIRTMEWIEQQRLHSFLMIAKGSCEPPVLMEITY 267
            :.::||..::|.:.|:  :.:.::....:|..|...|..::.::.|:|.:|..|..||..:.:.|
plant   270 LVNSPANVLSPAVLAEEASNLASMYSNVMTANILKEEQCKELKMGSYLAVAAASANPPHFIHLIY 334

  Fly   268 CGTNPEDKPI----LFLGKGITFNSGAMNLRKCRG----MEEYRACMSGAASCVAMMRCVAALAL 324
               .|...|:    ..:|||:||:||..|::  .|    :|..:..:.|:|:.:...:.:..:..
plant   335 ---KPSSGPVKTKLALVGKGLTFDSGGYNIK--IGPELIIELMKIDVGGSAAVLGAAKAIGEIKP 394

  Fly   325 P-INVCCIIPLCENMPSGMACKPGDVVTLMNHKS-----------------------MAVRNLDK 365
            | :.|..|:..||||.||...:||||:|..|.|:                       :.|.:.|.
plant   395 PGVEVHFIVAACENMISGTGMRPGDVITASNGKTIEVSLHRFHMNSASKGSSFPLLVLQVNDTDS 459

  Fly   366 AGVVVMADPLLY--GQSTYKPRLVVDVATLGSGVKKAFGGGATGIFSNSHYIWKQFQSAGALTGD 428
            .|.:.:||.|:|  .|...|   :||:|||...:..|.|....|:::.|..:.|:..:|...:|:
plant   460 EGRLTLADALVYACNQGVDK---IVDIATLTGEIIVALGPSMAGMYTASDELAKEVIAASQRSGE 521

  Fly   429 RVWRLPLWNYYRKQITDEMGYDLSNDGRGLANSCLAAAVLHELV-PCVDWAHLDTRGTGLLTKYG 492
            ::||:|:...|.:.:...:. |:.|.|.....|..||..|...| ..|:|.|:|..|.....|
plant   522 KLWRMPMEESYWEMMKSGVA-DMVNFGGRAGGSITAALFLKRFVSENVEWLHIDMAGRVWNEK-- 583

  Fly   493 LVPYLTAKYMTGRPTRTLAQFL 514
                  .|..||....||.:::
plant   584 ------KKAATGFGVATLVEWV 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap4	NP_729613.1	PRK00913	31..514	CDD:234863	131/540 (24%)
S-Lap4	NP_729613.1	Peptidase_M17	35..514	CDD:238247	131/540 (24%)
AT4G30910	NP_001328632.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1254
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1544
OMA	1	1.010	-	-		QHG61256
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	1	1.000	-	-		FOG0001058
OrthoInspector	1	1.000	-	-		mtm1057
orthoMCL	1	0.900	-	-		OOG6_100682
Panther	1	1.100	-	-	O	PTHR11963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X713
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840