DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment S-Lap4 and LAP1

DIOPT Version :9

Sequence 1:	NP_729613.1	Gene:	S-Lap4 / 326188	FlyBaseID:	FBgn0052064	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001118375.1	Gene:	LAP1 / 816954	AraportID:	AT2G24200	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	485	Identity:	133/485 - (27%)
Similarity:	215/485 - (44%)	Gaps:	59/485 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KG--LVVGVYQKE--NDNDPKL-TPAGEKVNDRLHGKLQEMICQSKITGHLGRGKIFNNIDPEFR 95
            ||  |||||.:|:  .|.:.|. .|...||:..|.|.|.::..:...||..|:..:........:
plant    31 KGDILVVGVTEKDLAKDGNSKFENPILSKVDAHLSGLLAQVSSEEDFTGKPGQSTVLRLPGLGSK 95

  Fly    96 SMAVVGVG---LEGIGFNEL----EMLDEGMENVRVAAGIGARSLQEIGVSEVFVDGMDYAEQAA 153
            .:|::|:|   ...:.|:.|    ..:.:..::...|..:.:....|..:|.|        ...|
plant    96 RIALIGLGQSVSSPVAFHSLGEAVATVSKASQSTSAAIVLASSVSDESKLSSV--------SALA 152

  Fly   154 EGAVLAVWRYCDMNSKRKPPHI---------------PKLELYESPDYEGWTRGVFKAEAQNLAR 203
            .|.||.::......|:.|.|.:               .||:..|...|     ||.      ..|
plant   153 SGIVLGLFEDGRYKSESKKPSLKAVDIIGFGTGAEVEKKLKYAEDVSY-----GVI------FGR 206

  Fly   204 RMCDTPACCMTPTLFAQ--ATVDALCPCGITVEIRTMEWIEQQRLHSFLMIAKGSCEPPVLMEIT 266
            .:.::||..:||.:.|:  |.|.:......|..|...|..::.::.|:|.:|..|..||..:.:.
plant   207 ELINSPANVLTPAVLAEEAAKVASTYSDVFTANILNEEQCKELKMGSYLAVAAASANPPHFIHLV 271

  Fly   267 YCGTNPEDKPILFL-GKGITFNSGAMNLRKCRG--MEEYRACMSGAASCVAMMRCVAALALP-IN 327
            |...|...|..|.| |||:||:||..|::...|  :|..:..|.|:|:.:...:.:..:..| :.
plant   272 YKPPNGSVKTKLALVGKGLTFDSGGYNIKTGPGCSIELMKFDMGGSAAVLGAAKAIGEIKPPGVE 336

  Fly   328 VCCIIPLCENMPSGMACKPGDVVTLMNHKSMAVRNLDKAGVVVMADPLLY--GQSTYKPRLVVDV 390
            |..|:..||||.||...:||||:|..|.|::.|.|.|..|.:.:||.|:|  .|...|   :||:
plant   337 VHFIVAACENMISGTGMRPGDVITASNGKTIEVNNTDAEGRLTLADALVYACNQGVDK---IVDL 398

  Fly   391 ATLGSGVKKAFGGGATGIFSNSHYIWKQFQSAGALTGDRVWRLPLWNYYRKQITDEMGYDLSNDG 455
            |||......|.|....||::.|..:.|:..:|...:|:::||:||...|.:.:...:. |:.|.|
plant   399 ATLTGACVIALGTSMAGIYTPSDELAKEVIAASERSGEKLWRMPLEESYWEMMKSGVA-DMVNTG 462

  Fly   456 RGLANSCLAAAVLHELV-PCVDWAHLDTRG 484
            .....|..||..|.:.| ..|.|.|:|..|
plant   463 GRAGGSITAALFLKQFVSEKVQWMHIDMAG 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap4	NP_729613.1	PRK00913	31..514	CDD:234863	133/485 (27%)
S-Lap4	NP_729613.1	Peptidase_M17	35..514	CDD:238247	133/485 (27%)
LAP1	NP_001118375.1	PRK00913	20..516	CDD:234863	133/485 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1254
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1544
OMA	1	1.010	-	-		QHG61256
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	1	1.000	-	-		FOG0001058
OrthoInspector	1	1.000	-	-		mtm1057
orthoMCL	1	0.900	-	-		OOG6_100682
Panther	1	1.100	-	-	O	PTHR11963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X713
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840