Protein Alignment S-Lap4 and Lap3

DIOPT Version :10

• Sequence 1: NP_729613.1
• Gene: S-Lap4 / 326188
• FlyBaseID: FBgn0052064
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_077754.3
• Gene: Lap3 / 66988
• MGIID: 1914238
• Length: 519
• Species: Mus musculus
• Alignment Length: 518
• Identity: 219/518 - (42%)
• Similarity: 307/518 - (59%)
• Gaps: 24/518 - (4%)

  Fly    11 VVQRRLPVSHLIQ--IRTACGGESKSSKGLVVGVYQKENDND-PKLTPAGEKVNDRLHGKLQEMI 72
            |..|||.|..|..  :.||     ..:||||:|:|.|:.|:| |:.|.|||..|..:.|||:||:
Mouse    12 VALRRLGVRGLWDRGLSTA-----DMTKGLVLGIYAKDKDDDLPQFTSAGESFNKLVSGKLREML 71

  Fly    73 CQSKITG---HLGRGKIFNNIDPEFRSMAVVGVGLEGIGFNELEMLDEGMENVRVAAGIGARSLQ 134
               .|:|   ..|:.:.|..:..:|.|:.|||:|....|.::.|...||.||:|.|...|.|.:|
Mouse    72 ---NISGPPLKAGKTRTFYGLHQDFPSVVVVGLGKRSAGVDDQENWHEGKENIRAAVAAGCRQVQ 133

  Fly   135 EIGVSEVFVDGMDYAEQAAEGAVLAVWRYCDMNSKRKPPHIPKLELYESPDYEGWTRGVFKAEAQ 199
            ::.:..|.||....|:.|||||||.::.|.|:..|:|.....|  |:.|.|.|.|.:||..|..|
Mouse   134 DLELPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKVAVSAK--LHGSGDLEAWEKGVLFASGQ 196

  Fly   200 NLARRMCDTPACCMTPTLFAQATVDAL--CPCGITVEIRTMEWIEQQRLHSFLMIAKGSCEPPVL 262
            ||||.:.::||..||||.||:.....|  ......|.||...|||:|.:.|||.:||||.||||.
Mouse   197 NLARHLMESPANEMTPTRFAEIIEKNLKSASSKTKVHIRPKSWIEEQEMGSFLSVAKGSEEPPVF 261

  Fly   263 MEITYCGT-NPEDKPILFLGKGITFNSGAMNLRKCRGMEEYRACMSGAASCVAMMRCVAALALPI 326
            :||.|.|: |..:.|::|:||||||:||.::::....|:..||.|.|||:..:.:...|.|.|||
Mouse   262 LEIHYMGSPNATEAPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPI 326

  Fly   327 NVCCIIPLCENMPSGMACKPGDVVTLMNHKSMAVRNLDKAGVVVMADPLLYGQSTYKPRLVVDVA 391
            |:..:.|||||||||.|.||||||...|.|::.|.|.|..|.:::||.|.|.. |:.|:::::.|
Mouse   327 NIIGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAH-TFNPKVIINAA 390

  Fly   392 TLGSGVKKAFGGGATGIFSNSHYIWKQFQSAGALTGDRVWRLPLWNYYRKQITDEMGYDLSNDGR 456
            ||...:..|.|.||||:|:||.::|.:...|...|||||||:||:.:|.:|:.|....|::|.|:
Mouse   391 TLTGAMDVALGSGATGVFTNSSWLWNKLFEASVETGDRVWRMPLFEHYTRQVIDCQLADVNNLGK 455

  Fly   457 -GLANSCLAAAVLHELVPCVDWAHLDTRGTGLLTKYGLVPYLTAKYMTGRPTRTLAQFLYQMA 518
             ..|.:|.|||.|.|.|....|||||.  .|::|....:||| .|.|:|||||||.:||.:.:
Mouse   456 YRSAGACTAAAFLREFVTHTKWAHLDI--AGVMTNKDEIPYL-RKGMSGRPTRTLIEFLLRFS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap4	NP_729613.1	Peptidase_M17_N	39..168	CDD:426984	51/132 (39%)
		Peptidase_M17	201..509	CDD:459978	139/311 (45%)
Lap3	NP_077754.3	Peptidase_M17	33..511	CDD:238247	209/486 (43%)