Protein Alignment scramb1 and PLSCR2

DIOPT Version :9

• Sequence 1: NP_648389.3
• Gene: scramb1 / 326186
• FlyBaseID: FBgn0052056
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_011511324.2
• Gene: PLSCR2 / 57047
• HGNCID: 16494
• Length: 325
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 142/324 - (43%)
• Similarity: 181/324 - (55%)
• Gaps: 48/324 - (14%)

  Fly    90 YMGGPGGQPPY----AGGPGGQPPYVGG----PGGQPHYGGGAPPPQAFGGYPPGPAGPGGPPNA 146
            ::.||.|...|    ||..|.|..::|.    ||.|..|            ..| |||..|
Human    39 HLPGPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDY------------LVP-PAGTAG---- 86

  Fly   147 FGGYPPGQPQQPIVTQPGMGPGMGPGMAPQGGPAGDWMSIPTGIPNCPRGLEYLTTIDQLLVKQK 211
                      .|:..|||         .|:|.|   ||..|....|||.|||||:.||.:|:.|:
Human    87 ----------IPVQNQPG---------RPEGVP---WMPAPPPPLNCPPGLEYLSQIDMILIHQQ 129

  Fly   212 VELLEAFTGFETNNKFTIKNALGQKVYFAAEDNDCCTRNCCGPARPFDMRVFDNFQQEVIHMHRP 276
            :||||....||::|.:.|||:.||::||||||.:.|.|||||.:|||.:|:.||..:|||.:.||
Human   130 IELLEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERP 194

  Fly   277 LACSSCLFPCCLQSIEVSAPPGNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDV 341
            |.|:.|..|||||.||:.||||..:|.:.|.|..|...|.|.|...:.|::|.||....|....|
Human   195 LRCNCCCCPCCLQEIEIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGV 259

  Fly   342 EFNVVSLTGE-KIGKISKQWSGLAREIFTDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFEK 404
            :|.:.||..: .:|:|||.|||..||.|||||.|||.||.||||:||||::||.||||.||||:
Human   260 DFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFER 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb1	NP_648389.3	Sox_C_TAD	<61..>129	CDD:288887	13/46 (28%)
		Scramblase	184..404	CDD:252175	115/220 (52%)
PLSCR2	XP_011511324.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	288	1.000	Domainoid score	I1579
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2483
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		mtm8657
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.930