DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scramb1 and si:ch211-71m22.5

DIOPT Version :9

Sequence 1:	NP_648389.3	Gene:	scramb1 / 326186	FlyBaseID:	FBgn0052056	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_693207.5	Gene:	si:ch211-71m22.5 / 564785	ZFINID:	ZDB-GENE-130531-65	Length:	277	Species:	Danio rerio

Alignment Length:	289	Identity:	139/289 - (48%)
Similarity:	176/289 - (60%)	Gaps:	27/289 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 GYPPGPAGPG----GPPNAFGGYPPGQPQQPIVTQPGMGPGMGPGMAPQGGPAGDWMSIPTGIP- 191
            |...|...||    .||....|:|||..:  :.|.|..|     .:|||         :|..:|
Zfish     5 GQTEGVNAPGVNVPMPPVYTIGHPPGVNE--VYTTPPTG-----YVAPQ---------VPAVMPV 53

  Fly   192 -----NCPRGLEYLTTIDQLLVKQKVELLEAFTGFETNNKFTIKNALGQKVYFAAEDNDCCTRNC 251
                 .||.||||||.:|||||.|||||:|...|:||||::.:||:|||:|:||||::..|:|..
Zfish    54 LDRPMGCPVGLEYLTQVDQLLVHQKVELMEVLMGWETNNQYVVKNSLGQQVFFAAEESHFCSRMF 118

  Fly   252 CGPARPFDMRVFDNFQQEVIHMHRPLACSSCLFPCCLQSIEVSAPPGNVIGTIEQEWSICSPSFR 316
            ||..|.|.:.:.||..|||:.:.|||.||||.||||||.:||.:|.|:.:|.:.|.|....|.|.
Zfish   119 CGSVRSFLLHIQDNMGQEVMTLSRPLKCSSCFFPCCLQELEVHSPSGSPLGYVTQSWHPYLPKFI 183

  Fly   317 ILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSL-TGEKIGKISKQWSGLAREIFTDADFFGINFPL 380
            |.|...:.|::|.||||....|.||.|.|:|| ....||:|||||||...|.|||||.||:.||:
Zfish   184 IHNERKEPVLKILGPFCDCKCCSDVNFEVMSLDESSVIGRISKQWSGFEAEAFTDADNFGLQFPM 248

  Fly   381 DLDVRMKAVLLGATFLIDAMFFEKAGNQE 409
            ||||::|||:|||.||||.||||....||
Zfish   249 DLDVKIKAVILGACFLIDFMFFEHTQKQE 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scramb1	NP_648389.3	Sox_C_TAD	<61..>129	CDD:288887
scramb1	NP_648389.3	Scramblase	184..404	CDD:252175	120/226 (53%)
si:ch211-71m22.5	XP_693207.5	Scramblase	51..271	CDD:252175	118/219 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	288	1.000	Domainoid score	I1533
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100156
Panther	1	1.100	-	-	O	PTHR23248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.920