Protein Alignment scramb1 and plscr2

DIOPT Version :10

• Sequence 1: NP_648389.3
• Gene: scramb1 / 326186
• FlyBaseID: FBgn0052056
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_012818771.1
• Gene: plscr2 / 100489273
• XenbaseID: XB-GENE-5819744
• Length: 283
• Species: Xenopus tropicalis
• Alignment Length: 295
• Identity: 161/295 - (54%)
• Similarity: 193/295 - (65%)
• Gaps: 27/295 - (9%)

  Fly   116 GQPHYGGGAPPPQ--AFGGYPPGPAGPGGPPNAFGGYPPG----QPQQPIVTQPGMGPGMGPGMA 174
            |.|..|.|.|..|  |:.||||       ..|.:|..|||    ||.|.:.||||:     ||.|
 Frog     6 GNPGLGYGNPEFQNAAYPGYPP-------QQNPYGYPPPGPYQFQPGQAMPTQPGV-----PGAA 58

  Fly   175 PQGGPAGDWMSIPTGIPNCPRGLEYLTTIDQLLVKQKVELLEAFTGFETNNKFTIKNALGQKVYF 239
                    ||.||...||||.|||||:.|||:||.|:|||||..||||||||:.|||:|||:|||
 Frog    59 --------WMPIPAANPNCPPGLEYLSQIDQILVHQQVELLEVLTGFETNNKYEIKNSLGQRVYF 115

  Fly   240 AAEDNDCCTRNCCGPARPFDMRVFDNFQQEVIHMHRPLACSSCLFPCCLQSIEVSAPPGNVIGTI 304
            |||:|||||||.|||:|||.|.:.||..:||:.:||||.||:|.||||||.:||.||||.|:|.:
 Frog   116 AAEENDCCTRNYCGPSRPFAMTIVDNTGREVMKLHRPLRCSACCFPCCLQKLEVQAPPGTVVGYV 180

  Fly   305 EQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSL-TGEKIGKISKQWSGLAREIF 368
            .|.|..|.|.|.|.:.....|::|.||......|.||.|.|:|: ....:|:|||||:|..:|||
 Frog   181 VQNWHPCLPKFTIQDEREQGVLKISGPCIPCRCCTDVNFEVMSVDESSVVGRISKQWAGSVKEIF 245

  Fly   369 TDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFE 403
            ||.|.|||.||:|||::.|||||||.||||.||||
 Frog   246 TDTDNFGIQFPMDLDIKTKAVLLGACFLIDFMFFE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb1	NP_648389.3	PHA03378	<12..187	CDD:223065	28/76 (37%)
		Scramblase	184..404	CDD:252175	134/221 (61%)
plscr2	XP_012818771.1	Scramblase	60..280	CDD:252175	132/219 (60%)