DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scramb1 and si:ch211-71m22.1

DIOPT Version :9

Sequence 1:	NP_648389.3	Gene:	scramb1 / 326186	FlyBaseID:	FBgn0052056	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001121867.1	Gene:	si:ch211-71m22.1 / 100149582	ZFINID:	ZDB-GENE-070705-193	Length:	263	Species:	Danio rerio

Alignment Length:	252	Identity:	137/252 - (54%)
Similarity:	168/252 - (66%)	Gaps:	6/252 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 PIVTQPGM-----GPGMGPGMAPQGGPAGDWMSIPTGIPNCPRGLEYLTTIDQLLVKQKVELLEA 217
            |:..||..     .||.|.|.|..|......|.:|.....||.||||||.||||||:|||||.|.
Zfish     9 PVELQPNKNAIHPAPGYGQGAAIPGHGQVVMMPVPQRPDGCPPGLEYLTQIDQLLVQQKVELAEV 73

  Fly   218 FTGFETNNKFTIKNALGQKVYFAAEDNDCCTRNCCGPARPFDMRVFDNFQQEVIHMHRPLACSSC 282
            ..|:|||||:.:||::||:|::.||:||||.|..|||.|.|.:.|.||..|||:.:.|||.|.||
Zfish    74 ILGWETNNKYIVKNSMGQQVFYVAEENDCCNRQFCGPLRSFVIHVQDNLGQEVMRLMRPLKCGSC 138

  Fly   283 LFPCCLQSIEVSAPPGNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVS 347
            ..|||||.:|:.:|||..||.:.|.|....|.|.|.|...:.|::||||||:...|.||.|:|:|
Zfish   139 FCPCCLQELEIQSPPGYPIGYVIQNWHPFLPKFTIQNEKKEAVLKIEGPFCSCRCCSDVNFDVLS 203

  Fly   348 L-TGEKIGKISKQWSGLAREIFTDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFE 403
            | ...|:|||||||:||.||.|||||.|||:||:||||::||||.||.||||.||||
Zfish   204 LDESTKVGKISKQWTGLVREAFTDADNFGISFPMDLDVKIKAVLFGACFLIDFMFFE 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scramb1	NP_648389.3	Sox_C_TAD	<61..>129	CDD:288887
scramb1	NP_648389.3	Scramblase	184..404	CDD:252175	128/221 (58%)
si:ch211-71m22.1	NP_001121867.1	Scramblase	40..260	CDD:252175	126/219 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	288	1.000	Domainoid score	I1533
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		otm25733
orthoMCL	1	0.900	-	-		OOG6_100156
Panther	1	1.100	-	-	LDO	PTHR23248
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1891
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.810