Protein Alignment CG32054 and SLC2A4

DIOPT Version :10

• Sequence 1: NP_729588.1
• Gene: CG32054 / 326185
• FlyBaseID: FBgn0052054
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001033.1
• Gene: SLC2A4 / 6517
• HGNCID: 11009
• Length: 509
• Species: Homo sapiens
• Alignment Length: 582
• Identity: 130/582 - (22%)
• Similarity: 214/582 - (36%)
• Gaps: 163/582 - (28%)

  Fly    48 SGYPQPGHSWNPPPPQ--------FGFSGYPPPPQQGYPPQFYGPPPGYGLPQATLPPNPPQQTI 104
            ||:.|.|.....||.|        ..||......|.||         ..|:      .|.||:.|
Human     3 SGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGY---------NIGV------INAPQKVI 52

  Fly   105 --TVNNSWYSRNQKNKPQSNAVGAAGLIFVSGGMNIAWSIGFRGVLHYKTTEHNFAAWFIGGIIG 167
              :.|.:|..|.....|.|         ...|.:...|::             :.|.:.:||:|.
Human    53 EQSYNETWLGRQGPEGPSS---------IPPGTLTTLWAL-------------SVAIFSVGGMIS 95

  Fly   168 AVISWFLINNVAKKYVLIFSSFLVMIGGILTTSTKNSGDATLAASY--------LDGIANGLVFA 224
            :.:...:...:.:|..::.::.|.::||.|      .|.|..||||        |.|..:||...
Human    96 SFLIGIISQWLGRKRAMLVNNVLAVLGGSL------MGLANAAASYEMLILGRFLIGAYSGLTSG 154

  Fly   225 PFMALAGEVSVSYMRGMVSASIEQMCFGLGIFL-QIIYTSTWNSTAYPSYNSFSAENMKGVLSII 288
            ......||::.:::||.: .::.|:...:||.: |::                ..|::.|..|:.
Human   155 LVPMYVGEIAPTHLRGAL-GTLNQLAIVIGILIAQVL----------------GLESLLGTASLW 202

  Fly   289 YGFLAL-IIGSLL-------CIESPVIMLAKNNDEQGAIDALRRLQRPYTLTNETFEQLAEHKKY 345
            ...|.| ::.:||       |.|||..:....|.|..|..:|:|| ..:...:....:|.:.|:.
Human   203 PLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRL-TGWADVSGVLAELKDEKRK 266

  Fly   346 LAQNKELSMGQSIGQAL---PTFIRLVF-----LRGLNAMSISKFVMIGFVYSFA--SPYGYVSP 400
            |.:.:.||:.|.:|...   |..|.:|.     |.|:||:         |.||.:  ...|...|
Human   267 LERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAV---------FYYSTSIFETAGVGQP 322

  Fly   401 SVGWFIGFGVCRWMGNFIATFCMESCGRKKPTLLGLI-VCS----------------VMSFV--- 445
            :.. .||.||...:...::...:|..||:...||||. :|.                .||:|
Human   323 AYA-TIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIV 386

  Fly   446 -VAGQFNIFTYNTGNNIMLLVFELF------AGIAFTATSPYLSEAFPLEVKQHFI---SFTFIG 500
             :.|....|....|.....:|.|||      |.:|....|.:.|         :||   .|.::.
Human   387 AIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTS---------NFIIGMGFQYVA 442

  Fly   501 EMLVFLVLTLIRWSSSGGANYFYVMGGLYLFGFF-FGLVCLPETRRTTLREAQDKFSKFISM 561
            |.:               ..|.:::..:.|.||| |..:.:||||..|..:....|.:..|:
Human   443 EAM---------------GPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32054	NP_729588.1	Pro-rich	<7..102	CDD:464580	15/61 (25%)
		MFS	157..555	CDD:475125	104/455 (23%)
SLC2A4	NP_001033.1	Interaction with SRFBP1. /evidence=ECO:0000269|PubMed:16647043	7..13		2/5 (40%)
		MFS_GLUT_Class1	26..474	CDD:340989	120/542 (22%)
		Dileucine internalization motif. /evidence=ECO:0000269|PubMed:8300557	489..490		0/1 (0%)