Protein Alignment CG32054 and SLC2A1

DIOPT Version :10

• Sequence 1: NP_729588.1
• Gene: CG32054 / 326185
• FlyBaseID: FBgn0052054
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 114/521 - (21%)
• Similarity: 198/521 - (38%)
• Gaps: 142/521 - (27%)

  Fly    98 NPPQQTIT--VNNSWYSRNQKNKPQSNAVGAAGLIFVSGGMNIAWSIGFRGVLHYKTTEHNFAAW 160
            |.||:.|.  .|.:|..|             .|...:...:...||:             :.|.:
Human    34 NAPQKVIEEFYNQTWVHR-------------YGESILPTTLTTLWSL-------------SVAIF 72

  Fly   161 FIGGIIGAVISWFLINNVAKKYVLIFSSFLVMIGGILTTSTK--NSGDATLAASYLDGIANGLV- 222
            .:||:||:......:|...::..::..:.|..:..:|...:|  .|.:..:...::.|:..||.
Human    73 SVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTT 137

  Fly   223 -FAPFMALAGEVSVSYMRGMVSASIEQMCFGLGIFLQIIY---TSTWNSTAYPSYNSFSAENMKG 283
             |.|.  ..||||.:.:||.: .::.|:...:||.:..::   :...|...:|.
Human   138 GFVPM--YVGEVSPTALRGAL-GTLHQLGIVVGILIAQVFGLDSIMGNKDLWPL----------- 188

  Fly   284 VLSIIYGFLALIIGSLL---CIESPVIMLAKNNDEQGAIDALRRLQRPYTLTNETFEQLAEHKKY 345
            :||||  |:..::..::   |.|||..:|...|:|..|...|::|:....:|::..|...|.::.
Human   189 LLSII--FIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251

  Fly   346 LAQNKE--LSMGQSIGQALPTFIRLVF-----LRGLNAM---SISKFVMIGFVYSFASPYGYVSP 400
            :.:.|.  |.:.:|.....|..|.:|.     |.|:||:   |.|.|...|           |..
Human   252 MREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAG-----------VQQ 305

  Fly   401 SVGWFIGFGVCRWMGNFIATFCMESCGRKKPTLLGL---IVCSV--------------MSFV--- 445
            .|...||.|:.......::.|.:|..||:...|:||   ..|::              ||::
Human   306 PVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIV 370

  Fly   446 -VAGQFNIFTYNTGNNIMLLVFELF------AGIAFTATSPYLSEAFPLEVKQHFI---SFTFIG 500
             :.|....|....|.....:|.|||      |.||....|.:.|         :||   .|.::.
Human   371 AIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTS---------NFIVGMCFQYVE 426

  Fly   501 EM---LVFLVLTLIRWSSSGGANYFYVMGGLYLFGFFFGLVCLPETRRTTLREAQDKFSKFISMG 562
            ::   .||::.|::                |.|| |.|....:|||:..|..|        |:.|
Human   427 QLCGPYVFIIFTVL----------------LVLF-FIFTYFKVPETKGRTFDE--------IASG 466

  Fly   563 F 563
            |
Human   467 F 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32054	NP_729588.1	Pro-rich	<7..102	CDD:464580	2/3 (67%)
		MFS	157..555	CDD:475125	101/450 (22%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	109/502 (22%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		114/521 (22%)