DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32052 and CG15533

DIOPT Version :9

Sequence 1:	NP_001303410.1	Gene:	CG32052 / 326184	FlyBaseID:	FBgn0044328	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_651791.2	Gene:	CG15533 / 43612	FlyBaseID:	FBgn0039768	Length:	692	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	123/505 - (24%)
Similarity:	197/505 - (39%)	Gaps:	99/505 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SDLHLDTLYSTQGDIYRSCWELARSVSGSNANSAASEPPGPFGHY-NCDSPWRLIESAVKTMKAK 95
            ||:|.|..| |.|.: .:|.|..............|:..|.:|.| :||.||...|||:.  .|.
  Fly   225 SDIHHDPYY-TPGSL-ATCAEPMCCQRNKETTEGTSDAAGYWGDYRDCDLPWHAFESALD--NAV 285

  Fly    96 QGDNVEFVLWTGDALSHSAQPLSEQKQHEILRNITELLGRSFSSQFIFPVLG-HE---------D 150
            .....:|:..|||.:.|.....|.:|...:|..::|.|..:|....::|.:| ||         :
  Fly   286 ANSKCDFIYQTGDIVDHMVWATSVEKNTMVLTKVSERLNAAFGDVPVYPCIGNHEPHPLNLFSPE 350

  Fly   151 G-------SGSYRRLGELWRHWLPSEALVTFDQGGYYSIEQTKSRLRIVALNTNFMRLDPDPDPR 208
            |       ...|..|...|..|||:|...|..:||||::...|. .||:|||:|....|.
  Fly   351 GVPDEISTKWLYEHLYNDWSKWLPAETKETILKGGYYTVVPRKG-FRIIALNSNDCYTDN----- 409

  Fly   209 ASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVLTKSKEKQETVYIVGHMPPGVDERH 273
                 .|...            |..|::   .|..|..:.|.::::..|.|:::.|:|.|.
  Fly   410 -----FWLYH------------SGTDKI---PQLQWFHDTLLEAEKNGEYVHVLTHIPSGD---- 450

  Fly   274 LGTQHNQLTFTERNNQRYLDMVRRFAPVIQGQFFGHLHSDTFRLIY-DAKGNP--ISWLMIAPSI 335
             ||..:  .:....|:    .|.||...|.|.|.||.|.|...:.| :.:|:|  ::|...|.:.
  Fly   451 -GTCWS--VWAREFNR----CVSRFRSTISGIFTGHSHKDELFVYYSEDEGHPTAVAWNGGAVTT 508

  Fly   336 VPRKAGIGSSNNPALRLYKFDTGSGQVLDYTQFWLDLPLANRANEPTWQPEYNLTHYYA---LPE 397
            .       |:.||..|.|..:..:..|.::..:..:|..||.  :|..|||:.|.:.:.   ..:
  Fly   509 Y-------SNKNPNYREYAVNPETYTVTNHWTWIYNLTAANL--KPDEQPEWFLEYEFIKEFTED 564

  Fly   398 ISAVALHNFAERFTGTD--LSWFTRYHRANAVRYHSGSACPGLCMLNHYC--AIT----RLDYDE 454
            :|...:....:.|....  :..:.||...:|....:| .|...|:....|  |:|    |...:|
  Fly   565 MSPAGISKLLDEFAENPELMRKYWRYRVTSADPQVNG-GCDRSCLAGSLCRAAVTINSERERCEE 628

  Fly   455 FR----ICLEKEQLALQGRAPAALMPT------------SWSWLLGVLAV 488
            .|    ..|:.|:......:..|..|:            ..|..||:|:|
  Fly   629 LREKLFASLDNEESTSSSGSTEATTPSPSTPGGNDDNDGGGSSTLGLLSV 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32052	NP_001303410.1	MPP_ASMase	28..351	CDD:277321	89/339 (26%)
CG15533	NP_651791.2	SapB	99..183	CDD:214797
		MPP_ASMase	221..517	CDD:277321	89/339 (26%)
		Metallophos	274..483	CDD:278574	64/247 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452743
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D369165at33208
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	1	1.000	-	-		otm46555
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10340
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850