DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32052 and Smpd1

DIOPT Version :9

Sequence 1:	NP_001303410.1	Gene:	CG32052 / 326184	FlyBaseID:	FBgn0044328	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001006998.1	Gene:	Smpd1 / 308909	RGDID:	1549719	Length:	627	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	137/514 - (26%)
Similarity:	199/514 - (38%)	Gaps:	135/514 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PGAQARIGYFWHISDLHLDTLYSTQGDIYRSCWE--LARSVSGSNANSAASEPPGPFGHYN-CDS 80
            |||......|  ::|||.|..|....|  .:|.:  ..|..||...||...  .|.:|.|: ||.
  Rat   192 PGAPVSRVLF--LTDLHWDHDYLEGTD--PNCADPLCCRRGSGWPPNSRTG--AGYWGEYSKCDL 250

  Fly    81 PWRLIESAVKTMKAKQGDNVEFVLWTGDALSHSAQPLSEQKQHEILRNITELLGRSFSSQFIFPV 145
            |.|.:||.:|.:  ......|.|.||||..:|.....|.|.|...|..||:|:.:......::|.
  Rat   251 PLRTLESLLKGL--GPAGPFEMVYWTGDIPAHDVWQQSRQDQLRALNTITDLVWKFLGPVPVYPA 313

  Fly   146 LG-HED------------GSGS----YRRLGELWRHWLPSEALVTFDQGGYYSIEQTKSRLRIVA 193
            :| ||.            |:.|    |..:.:.|..|||::||.|...||:|:: ..:..||:::
  Rat   314 VGNHESTPVNGFPPPFIKGNQSSQWLYEAMAKAWEPWLPADALHTLRIGGFYAL-TPRPGLRLIS 377

  Fly   194 LNTNFMR------LDPDPDPRASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVLTKS 252
            ||.||..      |....||...|.                               ||.:.|..:
  Rat   378 LNMNFCSRENFWLLINSTDPAGQLQ-------------------------------WLVDELQAA 411

  Fly   253 KEKQETVYIVGHMPPGVDERHLGTQHNQLTFTERNNQRYLDMVRRFAPVIQGQFFGHLHSDTFRL 317
            :.:.:.|:|:||:|||         |...::    :..|..::.|:...:.||||||.|.|.|.:
  Rat   412 ENRGDKVHIIGHIPPG---------HCLKSW----SWNYYKIIARYENTLAGQFFGHTHVDEFEI 463

  Fly   318 IYDAK--GNPISWLMIAPSIVPRKAGIGSSNNPALRLYKFD---TGSGQ-VLDYTQFWLDLPLAN 376
            .||.:  ..|::...:.||     |....:.||..|:|:.|   .||.. |||:..:.|:|..||
  Rat   464 FYDEETLSRPLAVAFLGPS-----ATTFINLNPGYRVYQIDGNYPGSSHVVLDHETYILNLTQAN 523

  Fly   377 R-ANEPTWQPEYNLTHYYALPEISAVALHNFAERFTGTD----LSWFTRYHRANAVRYHSG---- 432
            . ...|:|:..|.....|.||:....:.||...|....:    ..||.         ||.|
  Rat   524 APGGTPSWKRLYRARETYGLPDAMPASWHNLVYRMRADEQLFQTFWFL---------YHKGHPPS 579

  Fly   433 SACPGLCMLNHYCAITRLDYDEFRICLEKEQLALQGRAPAA---LMPTS--------WS 480
            ..|...|.|...||                ||:.:..:||.   |||..        ||
  Rat   580 EPCGTPCRLATLCA----------------QLSARADSPALCRHLMPNGSLPDAHSLWS 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32052	NP_001303410.1	MPP_ASMase	28..351	CDD:277321	94/350 (27%)
Smpd1	NP_001006998.1	SapB	85..158	CDD:214797
		MPP_ASMase	199..494	CDD:277321	94/352 (27%)
		Metallophos	252..459	CDD:278574	65/253 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53732
OrthoDB	1	1.010	-	-		D369165at33208
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830