DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32052 and asm-2

DIOPT Version :9

Sequence 1:	NP_001303410.1	Gene:	CG32052 / 326184	FlyBaseID:	FBgn0044328	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_509894.2	Gene:	asm-2 / 181323	WormBaseID:	WBGene00000212	Length:	618	Species:	Caenorhabditis elegans

Alignment Length:	477	Identity:	120/477 - (25%)
Similarity:	196/477 - (41%)	Gaps:	104/477 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 HISDLHLDTLY-----------STQGDIYRSCWELARSVSGSNAN---SAASEPPGPFG-HYNCD 79
            |:||:|:|..|           |..|.....|.:.::...|:..|   .....|.||:| .|.||
Worm   186 HLSDIHIDHQYVVGTEAYCQLDSALGTYAMCCRDYSQDSQGAPTNLKDKPIYVPAGPWGMPYLCD 250

  Fly    80 SPWRLIESAVKTMKAKQGDNVEFVLWTGDALSHSAQPLSEQKQHEILRNITELLGRSFSSQFIFP 144
            .|::..|||:|.: :|...::::::.|||..:|.:...:|....|.:.|:|.:....|....::.
Worm   251 LPYQTFESAMKHI-SKTFKDLDYIIITGDFEAHDSWDYTEDLTRENMNNMTNVFLEYFPGVPVYV 314

  Fly   145 VLGHEDG-------------------SGSYRRLGELWRHWLPSEALVTFDQGGYYSIEQTKSRLR 190
            .:|:.:|                   ...|:.:.|:|.||:|.|||.|......|:: ..|..|:
Worm   315 SIGNHEGVPQDAMAPHTMPEYDTRGPQWLYKIMSEMWSHWIPQEALDTVQYRASYAV-YPKPGLK 378

  Fly   191 IVALNT------NFMRLDPDPDPRASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVL 249
            :::|||      ||.....:.||.|:|.                               ||.|.|
Worm   379 LISLNTIYCSEFNFYLYVNEVDPDATLE-------------------------------WLIEEL 412

  Fly   250 TKSKEKQETVYIVGHMPPGVDERHLGTQHNQLTFTERNNQRYLDMVRRFAPVIQGQFFGHLHSDT 314
            ..|:.|.|.|:|:.|:|||.:....|...|           :.::|:|:...|...|:||.|.|.
Worm   413 QDSENKGELVHIISHIPPGDNYCLKGWSWN-----------FFEIVKRYENTIAQMFYGHTHYDQ 466

  Fly   315 FRLIY---DAKGNPISWLMIAPSIVPRKAGIGSSNNPALRLYKFDTG----SGQVLDYTQFWLDL 372
            |.:.|   |....|..:..|:||:...     ...|||.|:|:.|.|    :..|.|...::.::
Worm   467 FMVYYDMDDPNRRPFHFNWISPSLTTY-----DWLNPAYRIYEIDGGYEGATYTVKDAKTYFANV 526

  Fly   373 PLANRAN-EPTWQPEYNLTHYYALPEISAVALHNFAER-FTGTDLSWFTRYHRANAVRYHSGSAC 435
            ..||..| ||.|...|:...:|.:.:.|..:..:.::: :|.|.|  |..|.|. ..|.|..:.|
Worm   527 TEANMKNKEPEWVLSYDTREHYQMADFSPQSWSDLSDKLWTNTTL--FRDYVRL-YYRNHYNNEC 588

  Fly   436 --PGLCMLNHYCAITR-LDYDE 454
              ...|.....|.|.: ..|||
Worm   589 YTDYKCRYTFVCDIKKGRSYDE 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32052	NP_001303410.1	MPP_ASMase	28..351	CDD:277321	90/363 (25%)
asm-2	NP_509894.2	SapB	70..143	CDD:214797
		SapB_1	72..106	CDD:282970
		MPP_ASMase	184..501	CDD:277321	90/363 (25%)
		CpdA	251..555	CDD:224327	86/352 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53732
OrthoDB	1	1.010	-	-		D369165at33208
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R975
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860