DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32052 and asm-1

DIOPT Version :9

Sequence 1:	NP_001303410.1	Gene:	CG32052 / 326184	FlyBaseID:	FBgn0044328	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_495415.2	Gene:	asm-1 / 174131	WormBaseID:	WBGene00000211	Length:	564	Species:	Caenorhabditis elegans

Alignment Length:	457	Identity:	107/457 - (23%)
Similarity:	184/457 - (40%)	Gaps:	113/457 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 ISDLHLDTLYSTQGDIYRSCWELARSVSGSNANS------AASEPPGPFGHY----NCDSPWRLI 85
            ::|||:|..|              :..|.:|.:.      :.|||....|::    .||.|:..:
Worm   163 LTDLHVDFEY--------------KYPSEANCDDPVCCRVSVSEPKKAAGYWGSVGKCDIPFWTV 213

  Fly    86 ESAVKTMKAKQGDNVEFVLWTGDALSHSAQPLSEQKQHEILRNITELLGRSFSSQFIFPVLGHED 150
            |:.:..:  .:...::.|:.|||.::|.....|.::...:||.:..|:..:|.|..|:..||:.:
Worm   214 ENMLSHI--NKTHMIDMVIMTGDYINHVDWEYSIEEHLSVLRKLHRLVQNTFPSTPIYWALGNHE 276

  Fly   151 G-----------------SGSYRRLGELWRHWLPSEALVTFDQGGYYSIEQTKSRLRIVALNTNF 198
            |                 :..|:....:...||...|..:..:.|.|| .|....|:::.|||.|
Worm   277 GVPVNSFAPHSVDERFWPTWLYKEFQTMSGPWLSEGAKDSLLKRGSYS-TQVMDGLKLITLNTGF 340

  Fly   199 MRL--------DPDPDPRASLSLRWPAEYFAEPKASVSSISAEDELLAEQQWLWLEEVLTKSKEK 255
            ..:        ..|||                     ||:|            |..:.|.:|::|
Worm   341 CEVTNFFLYLNQSDPD---------------------SSMS------------WFVKELFESEKK 372

  Fly   256 QETVYIVGHMPPGVDERHLGTQHNQLTFTERNNQRYLDMVRRFAPVIQGQFFGHLHSDTFRLIYD 320
            .|.||::.|:|||..|...|...|           |..:::||:..|..|||||.|.|.|.:.|:
Worm   373 GEQVYVLAHIPPGDSECLEGWAFN-----------YYRVIQRFSSTIAAQFFGHDHLDYFTVFYE 426

  Fly   321 AKGN----PISWLMIAPSIVPRKAGIGSSNNPALRLYKFDT-GSGQVLDYTQFWLDLPLANRANE 380
            ...|    |||....:||:...:     ..|||.|:|:.|. ...:::|:|.::.||..|....:
Worm   427 DMHNVSSKPISVGYASPSVTTFE-----YQNPAYRIYEIDPYNKFKIVDFTTYYADLEKATEDKK 486

  Fly   381 PTWQPEYNLTHYYALPEISAVALHNFAER-FTG-TDLSWFTRYHRANAVRYHSGSACPGLCMLNH 443
            |.|:..|:....:.:.::|.::.:...:: ||. .....|.:|    |.|..| ..|...|.:..
Worm   487 PVWEKLYSARQAHGMDDLSPLSWNKVIQKLFTSEKKREKFYQY----AFRNFS-PQCDSTCQMQL 546

  Fly   444 YC 445
            .|
Worm   547 MC 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32052	NP_001303410.1	MPP_ASMase	28..351	CDD:277321	85/358 (24%)
asm-1	NP_495415.2	SapB	39..113	CDD:214797
		MPP_ASMase	160..456	CDD:277321	85/358 (24%)
		Metallophos	210..417	CDD:278574	58/253 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3770
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3862
OMA	1	1.010	-	-		QHG53732
OrthoDB	1	1.010	-	-		D369165at33208
OrthoFinder	1	1.000	-	-		FOG0000551
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R975
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.810