DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31988 and LPXN

DIOPT Version :9

Sequence 1:	NP_001286122.1	Gene:	CG31988 / 326182	FlyBaseID:	FBgn0051988	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001137467.1	Gene:	LPXN / 9404	HGNCID:	14061	Length:	391	Species:	Homo sapiens

Alignment Length:	168	Identity:	64/168 - (38%)
Similarity:	100/168 - (59%)	Gaps:	3/168 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CHKCQEAITKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCKK 71
            |..||:.|..::|.|||::||||||:|.||.|:|..:.|..:||...|...:.:.::..||.|..
Human   157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAA 221

  Fly    72 PILEKTICAMGESWHEDCFCCGGACKKPLANQTFYERDGKPYCKKDYEDLFAARCAKCEKPITDS 136
            |||:|.:.||.::||.:.|.| ..|.:....:.|:|:|.||||:||:..:|:.:|..|.:|:.::
Human   222 PILDKVLTAMNQTWHPEHFFC-SHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLEN 285

  Fly   137 AVLAMNVKWHRDCFRCNKCENPI-TSQTFTIDGDKPVC 173
            .:.||:..||.:||.|..|.... |...|.:|| :|.|
Human   286 YLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG-RPFC 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31988	NP_001286122.1	LIM	7..58	CDD:295319	23/50 (46%)
		LIM	66..118	CDD:295319	22/51 (43%)
		LIM	126..176	CDD:259829	17/49 (35%)
LPXN	NP_001137467.1	LIM1_Leupaxin	155..209	CDD:188790	23/51 (45%)
		LIM2_Leupaxin	216..267	CDD:188792	22/51 (43%)
		LIM3_Leupaxin	275..327	CDD:188794	17/49 (35%)
		LIM4_Paxillin_like	334..385	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840