DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31988 and LRG1

DIOPT Version :9

Sequence 1:	NP_001286122.1	Gene:	CG31988 / 326182	FlyBaseID:	FBgn0051988	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_010041.2	Gene:	LRG1 / 851358	SGDID:	S000002399	Length:	1017	Species:	Saccharomyces cerevisiae

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	79/196 - (40%)	Gaps:	28/196 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VCHKCQEAI------TKRMITALGKTWHPEHFLCHHCDEQILDATFNVQ---SGEPV--CNKCFV 59
            :|.:|.:.:      ||..:.||||.:|...|.|..|.:.:....|..|   :.|.:  |...:.
Yeast    27 ICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYF 91

  Fly    60 ERYTYTCAGCKKPILEKTICAMGESWHEDCFCCGGACKKPLANQTFYERDGKPYCKKDYEDLFAA 124
            .|:...|..|..|:......|.|..:.|:.|.| ..|..|...:..:....:.|||..:...|:.
Yeast    92 RRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSC-TICATPCGVKKCFMYGNQLYCKYHFLKYFSK 155

  Fly   125 RCAKCEKPITDSAVLAMNVK----WHRDCFRCNKCEN-PITSQTFTI-----------DGDKPVC 173
            ||..||.||:|..:.....:    ||.:|:..:|..: .:.::|..:           .|||.:.
Yeast   156 RCKGCEFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDIN 220

  Fly   174 P 174
            |
Yeast   221 P 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31988	NP_001286122.1	LIM	7..58	CDD:295319	16/61 (26%)
		LIM	66..118	CDD:295319	13/51 (25%)
		LIM	126..176	CDD:259829	15/65 (23%)
LRG1	NP_010041.2	LIM1_Lrg1p_like	28..90	CDD:188777	16/61 (26%)
		LIM	98..149	CDD:259829	13/51 (25%)
		LIM3_Lrg1p_like	419..475	CDD:188779
		RhoGAP_fLRG1	728..959	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	3	2.900