DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31988 and Tgfb1i1

DIOPT Version :9

Sequence 1:	NP_001286122.1	Gene:	CG31988 / 326182	FlyBaseID:	FBgn0051988	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	XP_006230411.1	Gene:	Tgfb1i1 / 84574	RGDID:	620173	Length:	473	Species:	Rattus norvegicus

Alignment Length:	168	Identity:	66/168 - (39%)
Similarity:	103/168 - (61%)	Gaps:	1/168 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VCHKCQEAITKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCK 70
            :|..|.:.|..:::||||:.||||||||..|...:..::|..:.|.|.|.:|:.||::..|..|.
  Rat   239 LCGSCNKPIAGQVVTALGRAWHPEHFLCRGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFCN 303

  Fly    71 KPILEKTICAMGESWHEDCFCCGGACKKPLANQTFYERDGKPYCKKDYEDLFAARCAKCEKPITD 135
            :||..|.:.|:|..||.:.||| .:|.:|...:.|:||:|:|||::|:..|||.||..|:.||.|
  Rat   304 QPIRHKMVTALGTHWHPEHFCC-VSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILD 367

  Fly   136 SAVLAMNVKWHRDCFRCNKCENPITSQTFTIDGDKPVC 173
            :.:.|::..||.|||.|.:|..|.:..:|.....:|:|
  Rat   368 NYISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLC 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31988	NP_001286122.1	LIM	7..58	CDD:295319	20/50 (40%)
		LIM	66..118	CDD:295319	21/51 (41%)
		LIM	126..176	CDD:259829	17/48 (35%)
Tgfb1i1	XP_006230411.1	Paxillin	<69..>118	CDD:281527
		LIM1_Paxillin_like	240..292	CDD:259830	21/51 (41%)
		LIM2_Paxillin_like	299..350	CDD:188723	21/51 (41%)
		LIM3_Paxillin	358..410	CDD:188793	17/48 (35%)
		LIM4_Leupaxin	417..468	CDD:188796
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840