DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31988 and FHL2

DIOPT Version :9

Sequence 1:	NP_001286122.1	Gene:	CG31988 / 326182	FlyBaseID:	FBgn0051988	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001034581.1	Gene:	FHL2 / 2274	HGNCID:	3703	Length:	279	Species:	Homo sapiens

Alignment Length:	177	Identity:	58/177 - (32%)
Similarity:	89/177 - (50%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CHKCQEAI---TKRMITALGKTWHPEHFLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAG 68
            |.:|::.|   |::| ...|.:||...|:||.|.:.|...:|..:..:..|..|:.:::...|..
Human   101 CQECKKTIMPGTRKM-EYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQ 164

  Fly    69 CKKPILEKTICAMGESWHEDCFCCGGACKKPLANQTFYERDGKPYCKKDYEDLFAARCAKCEKPI 133
            |||||....:....:.||::||.| .||:|.|:.|.|..||...||...:.||:|.:||.|..||
Human   165 CKKPITTGGVTYREQPWHKECFVC-TACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPI 228

  Fly   134 T----DSAVLAMNVKWHRDCFRCNKCENPITSQTFTIDGDKPVCPAC 176
            :    ...:.....:||.|||.|.||...:..:.|..:.|..:||.|
Human   229 SGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31988	NP_001286122.1	LIM	7..58	CDD:295319	15/53 (28%)
		LIM	66..118	CDD:295319	21/51 (41%)
		LIM	126..176	CDD:259829	17/53 (32%)
FHL2	NP_001034581.1	LIM	<5..33	CDD:413332
		LIM1_FHL2	36..97	CDD:188806
		LIM2_FHL2	101..157	CDD:188810	16/56 (29%)
		LIM3_Fhl2	162..218	CDD:188815	23/56 (41%)
		LIM4_FHL2	221..278	CDD:188817	18/55 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I4662
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104605
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.950