DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31988 and Fhl2

DIOPT Version :9

Sequence 1:	NP_001286122.1	Gene:	CG31988 / 326182	FlyBaseID:	FBgn0051988	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001276462.1	Gene:	Fhl2 / 14200	MGIID:	1338762	Length:	279	Species:	Mus musculus

Alignment Length:	215	Identity:	62/215 - (28%)
Similarity:	95/215 - (44%)	Gaps:	38/215 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTESIVCHKCQEAI-TKRMI------------------------TALG----------KTWHPEH 30
            |||...||.|.|:: .|:.|                        |.:|          :.||...
Mouse     1 MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGC 65

  Fly    31 FLCHHCDEQILDATFNVQSGEPVCNKCFVERYTYTCAGCKKPILEKT--ICAMGESWHEDCFCCG 93
            |.|..|...::|..|..:..:.:|..|:...|:..|..|||.|:..|  :...|.||||.||.|
Mouse    66 FHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTC- 129

  Fly    94 GACKKPLANQTFYERDGKPYCKKDYEDLFAARCAKCEKPITDSAVLAMNVKWHRDCFRCNKCENP 158
            ..|::|:..::|..::.:.:|...||..:|.:|.:|:||||...|......||::||.|..|:..
Mouse   130 QRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQ 194

  Fly   159 ITSQTFTIDGDKPVCPACNC 178
            ::.|.||...:.|.|..|.|
Mouse   195 LSGQRFTARDEFPYCLTCFC 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31988	NP_001286122.1	LIM	7..58	CDD:295319	16/85 (19%)
		LIM	66..118	CDD:295319	18/53 (34%)
		LIM	126..176	CDD:259829	18/49 (37%)
Fhl2	NP_001276462.1	LIM	<5..33	CDD:413332	6/27 (22%)
		LIM	36..97	CDD:413332	11/60 (18%)
		LIM	101..157	CDD:413332	20/56 (36%)
		LIM	162..218	CDD:413332	20/53 (38%)
		LIM4_FHL2	221..278	CDD:188817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4604
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104605
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950