DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31988 and LIMS4

DIOPT Version :9

Sequence 1:	NP_001286122.1	Gene:	CG31988 / 326182	FlyBaseID:	FBgn0051988	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001358269.1	Gene:	LIMS4 / 100288695	HGNCID:	39941	Length:	398	Species:	Homo sapiens

Alignment Length:	234	Identity:	65/234 - (27%)
Similarity:	89/234 - (38%)	Gaps:	65/234 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CHKCQEAITKRMITALGKTWHPEHFLCHHCDEQILDATFNVQS-----------------GEPVC 54
            ||:|.|.|..|:|.|:..:||||.|.|..|.|.:.|..|...:                 |:.:|
Human   133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYIC 197

  Fly    55 NKCFV-------------------------------------ERYTY---------TCAGCKKPI 73
            .||..                                     |.|..         .|..|::||
Human   198 QKCHAIIDEQPLIFKNDPYHPDHFNCANCGKDLTADAQELKGELYCLPCHDKMGVPICGACRRPI 262

  Fly    74 LEKTICAMGESWHEDCFCCGGACKKPLANQTFYERDGKPYCKKDYEDLFAARCAKCEKPITDSAV 138
            ..:.:.|||:.||.:.|.| ..|:||......|||.|..||:..|..||...|..|.:.|....|
Human   263 EGRVVNAMGKQWHVEHFVC-AKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVV 326

  Fly   139 LAMNVKWHRDCFRCNKCENPITSQTFTIDGD-KPVCPAC 176
            .|:|..|..:||.|:.|...:|.:...::.| ||||..|
Human   327 SALNKAWCVNCFACSTCNTKLTLKDKFVEIDLKPVCKHC 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31988	NP_001286122.1	LIM	7..58	CDD:295319	21/67 (31%)
		LIM	66..118	CDD:295319	20/51 (39%)
		LIM	126..176	CDD:259829	17/50 (34%)
LIMS4	NP_001358269.1	LIM1_PINCH	72..130	CDD:188717
		LIM2_PINCH	133..184	CDD:188718	18/50 (36%)
		LIM3_PINCH	197..247	CDD:188719	5/49 (10%)
		LIM4_PINCH	253..306	CDD:188720	20/53 (38%)
		LIM5_PINCH	314..367	CDD:188721	18/52 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010