Protein Alignment CG31937 and Hsd17b14

DIOPT Version :10

• Sequence 1: NP_608616.2
• Gene: CG31937 / 326177
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_079606.3
• Gene: Hsd17b14 / 66065
• MGIID: 1913315
• Length: 273
• Species: Mus musculus
• Alignment Length: 249
• Identity: 62/249 - (24%)
• Similarity: 103/249 - (41%)
• Gaps: 30/249 - (12%)

  Fly    46 GQVVWITGASSGIGRALALSLARHGVKLVL------SARRLEQLEQVQEECLAAARGLLATKDVL 104
            |:||.:||.|.|||.|:..:....|.::|.      ..|.|||                .....:
Mouse     9 GKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAGGRALEQ----------------ELSGTV 57

  Fly   105 VIQMDMLDLDEHKTHLNTVLNHFHRLDVLVNNAGRSQRASW-TEVEIEVDRELFELDVFAVVHLS 168
            .|..|:....:.:|.::..|:.|..||.:|||||....|.. .|...:..|:|.|:::.....|.
Mouse    58 FIPGDVTQERDLQTLVSETLSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEVNLLGTYTLI 122

  Fly   169 RLVVRYFVEQNGGRGHIAATSSIAGFSPVPFSPTYCAAKHALNAYLLSLKVEMRK--LDVSLFAP 231
            :|.:.:.   ...||:|...||:.|......:.||.|.|.|:.|...:|.::..:  :.|:..:|
Mouse   123 KLALPHL---RKSRGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISP 184

  Fly   232 GPIATDFLQE--AFTGSQGGKVGLSTANQKRMTAQRCGDLFAVALANKMDLTWC 283
            |.|.|...:|  |.|......:...|..|......:..::.|.|:....:.|:|
Mouse   185 GNIWTPLWEELAASTSDPRATILEGTLAQPLGRMGQPAEVAAAAVFLASEATFC 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31937	NP_608616.2	Rossmann-fold NAD(P)(+)-binding proteins	44..293	CDD:473865	62/249 (25%)
Hsd17b14	NP_079606.3	Rossmann-fold NAD(P)(+)-binding proteins	1..256	CDD:473865	62/249 (25%)