DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31937 and Hsdl2

DIOPT Version :10

Sequence 1:NP_608616.2 Gene:CG31937 / 326177 FlyBaseID:FBgn0031360 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_651578.1 Gene:Hsdl2 / 43325 FlyBaseID:FBgn0039537 Length:412 Species:Drosophila melanogaster


Alignment Length:269 Identity:60/269 - (22%)
Similarity:113/269 - (42%) Gaps:21/269 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 VSLSSMRGQVVWITGASSGIGRALALSLARHGVKLVLSARRLEQLEQVQEECLAAARGL-LATKD 102
            ::...:.|:.::|||||.|||:.:||..||.|..:|::|:..|...::.....:||..: .|...
  Fly     2 INTGKLAGRTLFITGASRGIGKEIALKAARDGANIVVAAKTAEPHPKLPGTIYSAAEEIEKAGGK 66

  Fly   103 VLVIQMDMLDLDEHKTHLNTVLNHFHRLDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHL 167
            .....:|:.|..:.::.:...:..|..:|:::|||......:..:.:::....:..::......:
  Fly    67 AYPCVVDVRDEQQVRSAVEAAVAKFGGIDIVINNASAISLTNTPDTDMKRYDLMHNINTRGTFLV 131

  Fly   168 SRLVVRYFVEQNGGRGHIAATSSIAGFSPVPFSP--TYCAAKHALNAYLLSLKVEMRKLDVSLFA 230
            |::.:.|..:.|  ..||...|......|..|.|  .|..||:.::..:|.:..|.:...:|:.|
  Fly   132 SKVCLPYLKKSN--HAHILNISPPLSMKPKWFGPHVAYTMAKYGMSMCVLGMAAEFKDEGISVNA 194

  Fly   231 PGP---IATDFLQEAFTGSQGGK------------VGLSTANQKRMTAQRCGDLFAVALANKMDL 280
            ..|   |.|..: |..||....|            ..:.|...::.|.|...|...:..|...||
  Fly   195 LWPRTAIHTAAI-EMLTGPDSAKWSRKPEIMADAAYAILTREPRQSTGQFFVDDEVLESAGITDL 258

  Fly   281 TWCGLFPVN 289
            |....|..|
  Fly   259 TEYACFREN 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31937NP_608616.2 Rossmann-fold NAD(P)(+)-binding proteins 44..293 CDD:473865 60/264 (23%)
Hsdl2NP_651578.1 PRK08278 7..277 CDD:181349 60/264 (23%)
SCP2 306..408 CDD:442486
Blue background indicates that the domain is not in the aligned region.

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