DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31937 and Dhrs7l1

DIOPT Version :9

Sequence 1:	NP_608616.2	Gene:	CG31937 / 326177	FlyBaseID:	FBgn0031360	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001013116.1	Gene:	Dhrs7l1 / 299131	RGDID:	1308036	Length:	324	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	106/303 - (34%)
Similarity:	163/303 - (53%)	Gaps:	19/303 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFLEFLLLLL--VLYYVVYVLLWILLDCNVALWYKSRFG-VSLSSMRGQVVWITGASSGIGRAL 62
            |...||.:|.|  :|..|:.:|.::.||.::.|...:..| ....::..:||||||||||||..|
  Rat     1 MMGFEFWMLALCALLLLVLGLLSFLWLDSDLTLLRAAWMGQCPEQALADKVVWITGASSGIGEEL 65

  Fly    63 ALSLARHGVKLVLSARRLEQLEQVQEECLAAARGLLATKDVLVIQMDMLDLDEHKTHLNTVLNHF 127
            |..|::.||.|||||||.::||:|:..||  ..|.|..||:||:.:|:.|...|.....|||..|
  Rat    66 AFQLSKLGVCLVLSARRGQELERVKRRCL--ENGNLKEKDILVLPLDLADTSSHDIATKTVLQEF 128

  Fly   128 HRLDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSIA 192
            .|:|:||||.|.:..:......:::.:.|.|::....|.|::.|:.:.:|:|  :|.|....|:.
  Rat   129 GRIDILVNNGGVAHASLVENTNMDIFKVLIEVNYLGTVSLTKCVLPHMMERN--QGKIVVMKSLV 191

  Fly   193 GFSPVPFSPTYCAAKHALNAYLLSLKVEM---RKLDVSLFAPGPIATDFLQEAFTG----SQGGK 250
            |..|.|....|.|:|.||..:...|:.|:   ..:.:|:..|||:.::..|.||||    ::..|
  Rat   192 GIVPRPLCSGYAASKLALRGFFDVLRTELFDYPGITLSMICPGPVHSNIFQNAFTGDFTETRLPK 256

  Fly   251 VGLSTANQKRMTAQRCGDLFAVALANKMDLTWCGLFPVNLLAY 293
            :.|.     :|...||..|..|:|||.::..|....||.|.||
  Rat   257 IPLF-----KMETSRCVQLILVSLANDLEDIWIANQPVLLRAY 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31937	NP_608616.2	NADB_Rossmann	44..293	CDD:304358	92/255 (36%)
CG31937	NP_608616.2	adh_short	47..245	CDD:278532	76/200 (38%)
Dhrs7l1	NP_001013116.1	11beta-HSD1_like_SDR_c	47..305	CDD:187593	94/257 (37%)
Dhrs7l1	NP_001013116.1	adh_short	50..247	CDD:278532	76/200 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354446
Domainoid	1	1.000	139	1.000	Domainoid score	I4662
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4148
OMA	1	1.010	-	-		QHG59790
OrthoDB	1	1.010	-	-		D429842at33208
OrthoFinder	1	1.000	-	-		FOG0004121
OrthoInspector	1	1.000	-	-		otm45183
orthoMCL	1	0.900	-	-		OOG6_104960
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.670