Protein Alignment CG31937 and DHRS7B

DIOPT Version :9

• Sequence 1: NP_608616.2
• Gene: CG31937 / 326177
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: XP_011522088.1
• Gene: DHRS7B / 25979
• HGNCID: 24547
• Length: 334
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 84/285 - (29%)
• Similarity: 134/285 - (47%)
• Gaps: 38/285 - (13%)

  Fly     1 MSFLEFLLLLLVLYYVVYVL-LWILLDCNVALWYKSRFGVSLSSMRGQVVWITGASSGIGRALAL 64
            |.|:....:|.:|:..:.|. |:.||.     |.:.:     :.:|..||.||||:||:|:..|.
Human    63 MDFITSTAILPLLFGCLGVFGLFRLLQ-----WVRGK-----AYLRNAVVVITGATSGLGKECAK 117

  Fly    65 SLARHGVKLVLSARRLEQLEQVQEECLAAARGLLATKDVLVIQMDMLDLDEHKTHLNTVLNHFHR 129
            .....|.||||..|....||::..|..|:....:.|....::..|:.|..........:|..|..
Human   118 VFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 182

  Fly   130 LDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSIAGF 194
            :|:||||||.|.|.:..:..::||:.:.|.:.|..|.|::.::...:::.  :|||.|.|||.|.
Human   183 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRR--QGHIVAISSIQGK 245

  Fly   195 SPVPFSPTYCAAKHALNAYLLSLKVEMR--KLDVSLFAPGPIATDFLQEAFT--GSQ-------- 247
            ..:||...|.|:|||..|:...|:.||.  :::|::.:||.|.|:....|.|  ||.
Human   246 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSSYGHHHSPG 310

  Fly   248 ----GGKVGLSTANQKRMTAQRCGD 268
                ||..|.|..         ||:
Human   311 PKPCGGGPGCSCC---------CGE 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31937	NP_608616.2	NADB_Rossmann	44..293	CDD:304358	75/241 (31%)
		adh_short	47..245	CDD:278532	66/201 (33%)
DHRS7B	XP_011522088.1	11beta-HSD1_like_SDR_c	97..>304	CDD:187593	69/208 (33%)
		adh_short	101..294	CDD:278532	64/194 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D429842at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820