DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31937 and Hsd11b1

DIOPT Version :9

Sequence 1:	NP_608616.2	Gene:	CG31937 / 326177	FlyBaseID:	FBgn0031360	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_038946302.1	Gene:	Hsd11b1 / 25116	RGDID:	2834	Length:	1274	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	73/260 - (28%)
Similarity:	119/260 - (45%)	Gaps:	32/260 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLWILLDCNVALWYKSRFGVSLSSMRGQVVWITGASSGIGRALALSLARHGVKLVLSARRLEQLE 84
            ||.:|:.| :..:|.:........::|:.|.:||||.||||.:|..|::.|..:||:||..|.|:
  Rat     5 LLPVLVLC-LGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQ 68

  Fly    85 QVQEECL----AAARGLLATKDVLVIQMDMLDLDEHKTHLNTVLNHFHRLDVLVNNAGRSQRASW 145
            :|...||    |:|..:..|.:      ||...:........:|.   .||:|:.|.......|.
  Rat    69 KVVSRCLELGAASAHYIAGTME------DMAFAERFVVEAGKLLG---GLDMLILNHITQTTMSL 124

  Fly   146 TEVEIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSIAGFSPVPFSPTYCAAKHAL 210
            ...:|...|...|::..:.|.||...:....:.||.   ||..||:||....|...:|.|:|.||
  Rat   125 FHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGS---IAIISSMAGKMTQPLIASYSASKFAL 186

  Fly   211 NAYLLSLKVE--MRKLDVSL------FAPGPIATDFLQEAFTGSQGGKVGLSTANQKRMTAQRCG 267
            :.:..:::.|  |.|::||:      |......|...|::|..:  |::.||...|:     .||
  Rat   187 DGFFSTIRKEHLMTKVNVSITLCVLGFIDTGRQTSASQDSFVNT--GRIQLSKGLQR-----DCG 244

Fly 268 267
Rat 245 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31937	NP_608616.2	NADB_Rossmann	44..293	CDD:304358	68/236 (29%)
CG31937	NP_608616.2	adh_short	47..245	CDD:278532	61/209 (29%)
Hsd11b1	XP_038946302.1	11beta-HSD1_like_SDR_c	28..327	CDD:187593	68/236 (29%)
		Smc	<482..>650	CDD:224117
		RT_nLTR_like	710..972	CDD:238827
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D906746at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920