DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31937 and dhrs7c

DIOPT Version :9

Sequence 1:	NP_608616.2	Gene:	CG31937 / 326177	FlyBaseID:	FBgn0031360	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_012826975.2	Gene:	dhrs7c / 100135266	XenbaseID:	XB-GENE-5956201	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	236	Identity:	63/236 - (26%)
Similarity:	119/236 - (50%)	Gaps:	18/236 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFLEFL---LLLLVLYYVVYVLLWILLDCNVALWYKSRFGVSLSSMRGQVVWITGASSGIGRAL 62
            |.||.||   ||:|.:..:||:...:     |.|       :|.|:::.:||.||.|.||:|:..
Frog     1 MGFLTFLIVPLLILGISGIVYIYREV-----VRL-------MSRSALKNKVVVITDAISGLGKEC 53

  Fly    63 ALSLARHGVKLVLSARRLEQLEQVQEECLAAARGLLATKDVLVIQMDMLDLDEHKTHLNTVLNHF 127
            :......|.:|||..:..|:||.:.:..::.|...:.....||: :|:.|::..:.....:.:.:
Frog    54 SRVFHSAGARLVLCGKTWEKLEALHDALISVADPSVTFTPKLVL-LDISDINNMEAMGKEIQDCY 117

  Fly   128 HRLDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSIA 192
            ..:|||:|||....:.....|.:|:|:::.:.:.|..:.|.:.::.:.:.:.  .|.|...::|.
Frog   118 GCVDVLINNASMKMKGPLQSVSLELDKKIMDANYFGPITLVKAILPHMISRR--TGQIVLVNTIQ 180

  Fly   193 GFSPVPFSPTYCAAKHALNAYLLSLKVEMRKLDVSLFAPGP 233
            |...|||...|.|:|||:..:...|:.|:.:.|||:....|
Frog   181 GKIGVPFRAAYAASKHAIQGFFDCLRAEVEEFDVSVSTVSP 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31937	NP_608616.2	NADB_Rossmann	44..293	CDD:304358	49/190 (26%)
CG31937	NP_608616.2	adh_short	47..245	CDD:278532	49/187 (26%)
dhrs7c	XP_012826975.2	11beta-HSD1_like_SDR_c	35..257	CDD:187593	49/190 (26%)
dhrs7c	XP_012826975.2	LAP2alpha	425..629	CDD:371604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D429842at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920